Hugo Mbatchou Ngahane Bertrand, Walter Pefura-Yone Eric, Maïmouna Mama, Malea Nganda Motto, Ubald Olinga, Adeline Wandji, Bruno Tengang, Emmanuel Nyankiyé, Emmanuel Afane Ze, Christopher Kuaban
Department of Internal Medicine, Douala general Hospital, Douala, Cameroon; Faculty of Medicine and Pharmaceutical sciences, University of Douala, Cameroon.
Jamot Hospital, Yaounde, Cameroon.
Pan Afr Med J. 2016 Mar 9;23:70. doi: 10.11604/pamj.2016.23.70.8434. eCollection 2016.
The goal of asthma treatment is to obtain and maintain a good control of symptoms. Investigating factors associated with inadequately control asthma could help in strategies to improve asthma control. This study aimed to determine the prevalence and factors associated with inadequately controlled asthma in asthma patients under chest specialist care.
A cross-sectional study was conducted from November 2012 to May 2013. Physician-diagnosed asthma patients aged 12 years and above were included. A questionnaire was used to collect demographic data, comorbidities, and medical history of asthma. Asthma control was assessed using the Asthma Control Test (ACT), with a score less than 20 for inadequately controlled asthma and a score greater or equal to 20 for controlled asthma. A multivariate analysis was used to identify factors associated with inadequately controlled asthma.
Overall, 243 patients were included in this study. Asthma was controlled in 141 patients (58%) and inadequately controlled in 102 (42%). The mean duration of asthma was 8 years with an interquartile range of 4 and 18 years. Forty-three participants (17.7%) were not under any controller medication while the mean ACT score was 19.3 ± 4.6. Independent associations were found between inadequately controlled asthma and female gender (OR 1.91; 95% CI 1.06-3.47) and obesity (OR 1.81; 1.01-3.27).
Asthma remains poorly controlled in a large proportion of asthma patients under specialist care in Cameroon. Educational programs for asthma patients targeting women and based on weight loss for obese patients may help in improving the control of asthma.
哮喘治疗的目标是实现并维持对症状的良好控制。研究与哮喘控制不佳相关的因素有助于制定改善哮喘控制的策略。本研究旨在确定在胸部专科医生护理下的哮喘患者中,哮喘控制不佳的患病率及相关因素。
于2012年11月至2013年5月进行了一项横断面研究。纳入年龄在12岁及以上、经医生诊断为哮喘的患者。使用问卷收集人口统计学数据、合并症和哮喘病史。采用哮喘控制测试(ACT)评估哮喘控制情况,哮喘控制不佳定义为ACT得分低于20分,哮喘得到控制定义为ACT得分大于或等于20分。采用多变量分析确定与哮喘控制不佳相关的因素。
本研究共纳入243例患者。141例患者(58%)的哮喘得到控制,102例(42%)控制不佳。哮喘的平均病程为8年,四分位间距为4至18年。43名参与者(17.7%)未使用任何控制药物,ACT平均得分为19.3±4.6。发现哮喘控制不佳与女性性别(比值比1.91;95%置信区间1.06 - 3.47)和肥胖(比值比1.81;1.01 - 3.27)之间存在独立关联。
在喀麦隆,很大一部分接受专科护理的哮喘患者的哮喘控制情况仍然较差。针对女性哮喘患者并基于肥胖患者减重的教育项目可能有助于改善哮喘控制。