Luriia E A, Kuznetsov S A, Genkina E N, Fridenshteĭn A Ia
Biull Eksp Biol Med. 1989 May;107(5):593-5.
Bone formation in adult human bone marrow organ cultures is described. When culturing marrow fragments, thick bone lamina is formed. It has well-mineralized trabecular bone matrix with bone cells incorporated and is lined with osteoblast-like cells. In cultures of marrow deaggregated cell suspensions thin layers of the bone are only formed. Osteoclast-like cells develop in the cultures.
描述了成人骨髓器官培养中的骨形成。培养骨髓片段时,会形成厚的骨板。它具有矿化良好的小梁骨基质,其中包含骨细胞,并内衬有成骨细胞样细胞。在骨髓解聚细胞悬液培养中,仅形成薄层骨。培养中会发育出破骨细胞样细胞。