[骨髓器官培养中的骨形成]
[Bone formation in bone marrow organ cultures].
作者信息
Luriia E A, Owen M, Fridenshteĭn A Ia, Kuznetsov S A, Genkina E N
出版信息
Biull Eksp Biol Med. 1986 Apr;101(4):481-4.
PMID:3697499
Abstract
Bone tissue composed of typical bone trabeculae containing ground substance with incorporated osteogenic cells and osteoblast layer was formed in organ cultures of bone marrow obtained from adult mice. Electron microscopic properties of the bone formed in vitro were identical to those of the bone tissue in vivo. The mineralization of the bone took place only in the presence of Na-beta-glycerophosphate in the culture medium.
摘要
从成年小鼠获得的骨髓器官培养物中形成了由典型骨小梁组成的骨组织，骨小梁含有基质以及其中所含的成骨细胞和成骨细胞层。体外形成的骨的电子显微镜特性与体内骨组织的特性相同。骨的矿化仅在培养基中存在β-甘油磷酸钠的情况下发生。
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