Broz Pavel, Rajdl Daniel, Racek Jaroslav, Zenkova Jana, Petrikova Vlasta
Clin Chem Lab Med. 2017 Jan 1;55(1):47-52. doi: 10.1515/cclm-2016-0143.
Pneumatic tube systems (PTS) are widely used in many hospitals. Using PTS reduces turnaround time (TAT) and can improve patients' outcome.
We investigated whether clinically significant differences could be observed in CSF samples transported by pneumatic tube in comparison with samples transported by hand. Two aliquots from one sample were sent by PTS and by hand from the department of neurology or neurosurgery and compared.
Routine cytological and biochemical assessment was compared in 27 cases. There were no statistically significant changes (transport by hand vs. PTS) in glucose levels [data are expressed as median (minimum-maximum)] at 3.7 (2.5-8.6) mmol/L vs. 3.6 (2.7-8.6) mmol/L, p=0.96 or lactate levels at 1.8 mmol/L (1.1-5.5) vs. 1.8 mmol/L (1.1-5.4). We observed a statistically significant decline in total protein levels in samples transported by PTS at 0.56 g/L (0.19-4.29) vs. 0.49 g/L (0.18-4.3), p=0.008. We observed no changes in erythrocyte count at 5/μL (0-40,000) vs. 5/μL (0-40,106), mononuclear cells at 2/μL (1-145) vs. 3/μL (1-152), or polynuclear cells at 0/μL (0-235) vs. 0/μL (0-352). Spectrophotometric examination was performed in 20 cases. There were no statistically significant differences (transport by hand vs. transport by PTS) in NOA at 0.002 (0.001-1.537) vs. 0.001 (0.001-1.528), p=0.95 or NBA at 0.001 (0.001-0.231) vs. 0.001 (0.001-0.276), p=0.675. Samples transported by PTS were delivered faster than samples transported by courier (transport by hand vs. PTS) at 25 min (10-153) vs. 15 min (4-110), p=0.002.
We found no significant changes in glucose, lactate levels and in any of the cytological parameters assessed, nor were statistically significant changes observed in the spectrophotometric parameters. We found a statistically significant decrease in total protein levels in samples transported by PTS. Transport by PTS can be faster than transport by hand.
气动管道系统(PTS)在许多医院中广泛使用。使用PTS可缩短周转时间(TAT)并改善患者预后。
我们调查了与手工运送的样本相比,通过气动管道运送的脑脊液样本中是否能观察到具有临床意义的差异。将来自一个样本的两份等分试样分别通过PTS和由神经内科或神经外科手工运送并进行比较。
对27例病例的常规细胞学和生化评估进行了比较。葡萄糖水平[数据以中位数(最小值 - 最大值)表示]在手工运送组为3.7(2.5 - 8.6)mmol/L,在PTS运送组为3.6(2.7 - 8.6)mmol/L,p = 0.96;乳酸水平在手工运送组为1.8 mmol/L(1.1 - 5.5),在PTS运送组为1.8 mmol/L(1.1 - 5.4),两组间均无统计学显著变化。我们观察到PTS运送的样本中总蛋白水平有统计学显著下降,分别为0.56 g/L(0.19 - 4.29)和0.49 g/L(0.18 - 4.3),p = 0.008。红细胞计数在手工运送组为5/μL(0 - 40,000),在PTS运送组为5/μL(0 - 40,106);单核细胞计数在手工运送组为2/μL(1 - 145),在PTS运送组为3/μL(1 - 152);多核细胞计数在手工运送组为0/μL(0 - 235),在PTS运送组为0/μL(0 - 352),均未观察到变化。对20例病例进行了分光光度检查。在一氧化氮(NOA)方面,手工运送组为0.002(0.001 - 1.537),PTS运送组为0.001(0.001 - 1.528),p = 0.95;在神经氨酸酶(NBA)方面,手工运送组为0.001(0.001 - 0.231),PTS运送组为0.001(0.001 - 0.276),p = 0.675,两组间均无统计学显著差异。PTS运送的样本比快递运送的样本(手工运送与PTS运送)更快送达,分别为25分钟(10 - 153)和15分钟(4 - 110),p = 0.002。
我们发现葡萄糖、乳酸水平以及所评估的任何细胞学参数均无显著变化,分光光度参数也未观察到统计学显著变化。我们发现PTS运送的样本中总蛋白水平有统计学显著下降。PTS运送比手工运送更快。