Lee Johnson C, Lorenc Z Paul
Private Practice, Enhance Medical Center, 462 North Linden Drive, Suite 333, Beverly Hills, CA 90212, USA.
Lorenc Aesthetic Plastic Surgery Center, 983 Park Avenue, New York, NY 10028, USA.
Clin Plast Surg. 2016 Jul;43(3):497-503. doi: 10.1016/j.cps.2016.03.002.
Soft tissue filler procedures have increased dramatically in popularity in the United States. Synthetic fillers such as calcium hydroxyapatite (CaHA), polymethyl methacrylate (PMMA), and poly-l-lactic acid (PLLA), and silicone provide initial volume replacement but have an additional biostimulatory effect to supplement facial volumization. Indications include human immunodeficiency virus lipoatrophy and nasolabial folds for CaHA and PLLA and atrophic acne scars for PMMA. Most clinical use of these synthetic fillers is in an off-label fashion. Beyond the proper choice of a synthetic filler, careful consideration of dilution, injection method, and postprocedural care allows for successful and consistent results.
在美国，软组织填充手术的受欢迎程度急剧上升。合成填充剂，如羟基磷灰石钙（CaHA）、聚甲基丙烯酸甲酯（PMMA）、聚左旋乳酸（PLLA）和硅胶，可提供初始的体积填充，并有额外的生物刺激作用以补充面部容积。适应证包括CaHA和PLLA用于人类免疫缺陷病毒脂肪萎缩和鼻唇沟，PMMA用于萎缩性痤疮瘢痕。这些合成填充剂的大多数临床应用属于超适应证使用。除了正确选择合成填充剂外，仔细考虑稀释、注射方法和术后护理可获得成功且一致的效果。
