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不使用缝线/纤维蛋白胶的羊膜移植术

Amniotic membrane transplantation (AMT) without the use of sutures/fibrin glue.

作者信息

Agrawal Ajai, Pratap V B

出版信息

Nepal J Ophthalmol. 2015 Jul;7(14):173-7. doi: 10.3126/nepjoph.v7i2.14969.

DOI:10.3126/nepjoph.v7i2.14969
PMID:27363963
Abstract

INTRODUCTION

Amniotic membrane transplantation (AMT) has been used for a wide variety of ocular surface problems. Current techniques for the AMT involve suturing of the graft or patch over the ocular surface or use of fibrin glue.

OBJECTIVE

To describe a new sutureless technique of amniotic membrane transplantation (AMT) without the use of sutures/fibrin glue.

MATERIALS AND METHODS

Amniotic membrane transplantation as overlay or patch was done in fourteen eyes of eight patients with severe dry eye due to Stevens Johnson syndrome for ocular surface reconstruction, promotion of epithelization, reduction of inflammation and symptomatic relief from dry eye. In this new technique of amniotic membrane transplantation, we mount the amniotic membrane with its epithelial side up on a conformer and place it on the ocular surface without applying any sutures.

CONCLUSION

In all the fourteen eyes of eight patients operated at our centre, the amniotic membrane take up was satisfactory, with significant reduction of inflammation and symptomatic relief from dry eye. This is a simple, fast effective technique with surgical outcomes comparable to amniotic membrane transplantation using sutures/ fibrin glue.

摘要

引言

羊膜移植(AMT)已被用于多种眼表问题。目前羊膜移植技术包括将移植物或补片缝合在眼表或使用纤维蛋白胶。

目的

描述一种不使用缝线/纤维蛋白胶的新型无缝线羊膜移植(AMT)技术。

材料与方法

对8例因史蒂文斯-约翰逊综合征导致严重干眼的患者的14只眼进行羊膜移植作为覆盖物或补片,用于眼表重建、促进上皮化、减轻炎症以及缓解干眼症状。在这种新型羊膜移植技术中,我们将羊膜上皮面朝上放置在一个塑形器上,然后将其放置在眼表,不使用任何缝线。

结论

在我们中心接受手术的8例患者的14只眼中,羊膜的贴合情况令人满意,炎症明显减轻,干眼症状得到缓解。这是一种简单、快速有效的技术,手术效果与使用缝线/纤维蛋白胶的羊膜移植相当。

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Korean J Ophthalmol. 2025 Jun;39(3):288-299. doi: 10.3341/kjo.2025.0004. Epub 2025 May 28.
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Update on the application of amniotic membrane in immune-related ocular surface diseases.羊膜在免疫相关性眼表疾病中的应用进展
Taiwan J Ophthalmol. 2021 Jun 2;11(2):132-140. doi: 10.4103/tjo.tjo_16_21. eCollection 2021 Apr-Jun.