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食用盾叶酸模和拟长生草的酚类化合物及其生物效应:具有健康益处的天然物质潜在来源

Phenolic compounds and biological effects of edible Rumex scutatus and Pseudosempervivum sempervivum: potential sources of natural agents with health benefits.

作者信息

Savran Ahmet, Zengin Gokhan, Aktumsek Abdurrahman, Mocan Andrei, Glamoćlija Jasmina, Ćirić Ana, Soković Marina

机构信息

Department of Biology, Faculty of Science and Arts, Nigde University, Nigde, Turkey.

Department of Biology, Faculty of Science, Selcuk University, Konya, Turkey.

出版信息

Food Funct. 2016 Jul 13;7(7):3252-62. doi: 10.1039/c6fo00695g.

DOI:10.1039/c6fo00695g
PMID:27364042
Abstract

The present study outlines a chemical characterization and further effects beneficial to health of edible Rumex scutatus and Pseudosempervivum sempervivum, in addition to presenting the antioxidant, enzyme inhibitory effects and antimicrobial properties of different extracts. The phenolic compounds composition of the extracts was assessed by RP-HPLC-DAD, outlining benzoic acid and rutin as major constituents in P. sempervivum and rutin and hesperidin in R. scutatus. Moreover, further biological effects were tested on key enzymes involved in diabetes mellitus, Alzheimer's disease and skin melanogenesis revealing an important tyrosinase inhibitory effect of Pseudosempervivum water extract. Moreover, both species possessed antimicrobial properties towards bacteria and fungi relevant to public health. Accordingly, we find that R. scutatus and P. sempervivum can be considered as novel functional foods because they are rich sources of biologically active compounds that provide health benefits.

摘要

本研究概述了可食用皱叶酸模和长生草的化学特征及其对健康的进一步有益影响,此外还介绍了不同提取物的抗氧化、酶抑制作用和抗菌特性。通过反相高效液相色谱-二极管阵列检测法(RP-HPLC-DAD)评估提取物中的酚类化合物组成,结果表明长生草中的主要成分是苯甲酸和芦丁,而皱叶酸模中的主要成分是芦丁和橙皮苷。此外,还对参与糖尿病、阿尔茨海默病和皮肤黑色素生成的关键酶进行了进一步的生物学效应测试,结果显示长生草水提取物具有重要的酪氨酸酶抑制作用。此外,这两个物种对与公共卫生相关的细菌和真菌均具有抗菌特性。因此,我们发现皱叶酸模和长生草可被视为新型功能性食品,因为它们富含具有健康益处的生物活性化合物。

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