Kar Sujita Kumar, Jain Meha
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
District Mental Health Program, National Health Mission, Raebareli, Uttar Pradesh, India.
J Neurosci Rural Pract. 2016 Jul-Sep;7(3):412-8. doi: 10.4103/0976-3147.176185.
Schizophrenia is a severe mental disorder. Cognitive deficits are one of the core features of schizophrenia. Multiple domains of cognition (executive function, attention/vigilance, working memory, verbal fluency, visuospatial skills, processing speed, and social cognition) are affected in patients with schizophrenia. Deficits in cognition led to impairment in the real world functioning. Identifying the cognitive deficits and early intervention is required for better functional outcome. This review focuses on conceptual understanding of cognition with its neurobiological correlates in schizophrenia and its different clinical implications.
精神分裂症是一种严重的精神障碍。认知缺陷是精神分裂症的核心特征之一。精神分裂症患者的多个认知领域(执行功能、注意力/警觉性、工作记忆、语言流畅性、视觉空间技能、处理速度和社会认知)都会受到影响。认知缺陷导致现实世界功能受损。为了获得更好的功能结果,需要识别认知缺陷并进行早期干预。本综述重点关注对精神分裂症中认知及其神经生物学相关性的概念理解及其不同的临床意义。