Cho Jong Tae, Han Jin Hyung
Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea .
J Korean Med Sci. 2016 Jul;31(7):1164-7. doi: 10.3346/jkms.2016.31.7.1164. Epub 2016 May 9.
Mushroom exposures are increasing worldwide. The incidence and fatality of mushroom poisoning are reported to be increasing. Several new syndromes in mushroom poisoning have been described. Rhabdomyolytic mushroom poisoning is one of new syndromes. Russula subnigricans mushroom can cause delayed-onset rhabdomyolysis with acute kidney injury in the severely poisoned patient. There are few reports on the toxicity of R. subnigricans. This report represents the first record of R. subnigricans poisoning with rhabdomyolysis in Korea, describing a 51-year-old man who suffered from rhabdomyolysis, acute kidney injury, severe hypocalcemia, respiratory failure, ventricular tachycardia, cardiogenic shock, and death. Mushroom poisoning should be considered in the evaluation of rhabdomyolysis of unknown cause. Furthermore, R. subnigricans should be considered in the mushroom poisoning with rhabdomyolysis.
全球范围内蘑菇中毒事件呈上升趋势。据报道，蘑菇中毒的发病率和死亡率都在增加。已经描述了几种蘑菇中毒的新综合征。横纹肌溶解型蘑菇中毒是新综合征之一。亚黑红菇可导致严重中毒患者出现迟发性横纹肌溶解并伴有急性肾损伤。关于亚黑红菇毒性的报道很少。本报告是韩国首例亚黑红菇中毒伴横纹肌溶解的记录，描述了一名51岁男性，他患有横纹肌溶解、急性肾损伤、严重低钙血症、呼吸衰竭、室性心动过速、心源性休克并最终死亡。在评估不明原因的横纹肌溶解时应考虑蘑菇中毒。此外，在伴有横纹肌溶解的蘑菇中毒中应考虑亚黑红菇。
