Jang Hee-Chang, Park Wan Beom, Kim Uh Jin, Chun June Young, Choi Su-Jin, Choe Pyoeng Gyun, Jung Sook-In, Jee Youngmee, Kim Nam-Joong, Choi Eun Hwa, Oh Myoung-Don
Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea .
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
J Korean Med Sci. 2016 Jul;31(7):1173-7. doi: 10.3346/jkms.2016.31.7.1173. Epub 2016 May 27.
Since Zika virus has been spreading rapidly in the Americas from 2015, the outbreak of Zika virus infection becomes a global health emergency because it can cause neurological complications and adverse fetal outcome including microcephaly. Here, we report clinical manifestations and virus isolation findings from a case of Zika virus infection imported from Brazil. The patient, 43-year-old Korean man, developed fever, myalgia, eyeball pain, and maculopapular rash, but not neurological manifestations. Zika virus was isolated from his semen, and reverse-transcriptase PCR was positive for the virus in the blood, urine, and saliva on the 7th day of the illness but was negative on the 21st day. He recovered spontaneously without any neurological complications. He is the first case of Zika virus infection in Korea imported from Brazil.
自2015年寨卡病毒在美洲迅速传播以来，寨卡病毒感染的爆发已成为全球卫生紧急事件，因为它可导致神经并发症及包括小头畸形在内的不良胎儿结局。在此，我们报告一例从巴西输入的寨卡病毒感染病例的临床表现及病毒分离结果。该患者为一名43岁的韩国男性，出现发热、肌痛、眼球疼痛及斑丘疹，但无神经症状。从其精液中分离出寨卡病毒，发病第7天时血液、尿液及唾液的逆转录酶聚合酶链反应检测呈病毒阳性，但第21天时转为阴性。他未经任何神经并发症而自然康复。他是韩国首例从巴西输入的寨卡病毒感染病例。
