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妊娠期高甘油三酯血症所致急性胰腺炎

Acute Pancreatitis Due to Hypertriglyceridaemia in Pregnancy.

作者信息

Gök Funda, Köker Selçuk, Kılıçaslan Alper, Sarkılar Gamze, Yosunkaya Alper, Otelcioğlu Şeref

机构信息

Department of Anaesthiology and Reanimation, Necmettin Erbakan University Meram Faculty of Medicine, Konya, Turkey.

出版信息

Turk J Anaesthesiol Reanim. 2015 Apr;43(2):116-8. doi: 10.5152/TJAR.2014.83435. Epub 2015 Feb 5.

Abstract

Acute pancreatitis due to hypertriglyceridaemia during pregnancy is a rare but severe clinical condition that may cause fatal results for both the mother and the foetus. Acute pancreatitis developed in a 37-year-old pregnant woman with familial hypertriglyceridaemia and diabetes mellitus in the 31(st) week of pregnancy. As intrauterine foetal death developed, the pregnancy of the patient was terminated. Additionally, insulin, octreotide and plasmapheresis with "double membrane filtration" were applied, and triglycerides rapidly decreased. After 24 hours, the level of triglycerides decreased from 9742 mg dL(-1) to 432 mg dL(-1). The patient was discharged from the intensive care unit at the end of 5 days and was discharged from the hospital after 32 days. The current article presents the successful treatment of severe hypertriglyceridaemia in a pregnant case.

摘要

妊娠期高甘油三酯血症所致急性胰腺炎是一种罕见但严重的临床病症,可能对母亲和胎儿都造成致命后果。一名37岁患有家族性高甘油三酯血症和糖尿病的孕妇在妊娠31周时发生了急性胰腺炎。由于出现了宫内胎儿死亡,终止了该患者的妊娠。此外,应用了胰岛素、奥曲肽和采用“双重膜过滤”的血浆置换术,甘油三酯迅速下降。24小时后,甘油三酯水平从9742 mg dL⁻¹降至432 mg dL⁻¹。患者在5天后从重症监护病房出院,并在32天后出院。本文介绍了一例成功治疗妊娠期严重高甘油三酯血症的病例。

相似文献

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Acute Pancreatitis Due to Hypertriglyceridaemia in Pregnancy.妊娠期高甘油三酯血症所致急性胰腺炎
Turk J Anaesthesiol Reanim. 2015 Apr;43(2):116-8. doi: 10.5152/TJAR.2014.83435. Epub 2015 Feb 5.
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Management of hypertriglyceridaemia-induced acute pancreatitis in pregnancy.妊娠期高甘油三酯血症性急性胰腺炎的管理
J Matern Fetal Neonatal Med. 2015 May;28(8):954-8. doi: 10.3109/14767058.2014.939064. Epub 2014 Aug 5.

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本文引用的文献

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Issues in hypertriglyceridemic pancreatitis: an update.高甘油三酯血症性胰腺炎相关问题:最新研究进展
J Clin Gastroenterol. 2014 Mar;48(3):195-203. doi: 10.1097/01.mcg.0000436438.60145.5a.
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Therapeutic apheresis for severe hypertriglyceridemia in pregnancy.妊娠重度高甘油三酯血症的治疗性血液清除。
Arch Gynecol Obstet. 2013 May;287(5):839-43. doi: 10.1007/s00404-013-2786-z. Epub 2013 Mar 12.
3
Clinical study on acute pancreatitis in pregnancy in 26 cases.26 例妊娠合并急性胰腺炎的临床研究。
Gastroenterol Res Pract. 2012;2012:271925. doi: 10.1155/2012/271925. Epub 2012 Nov 18.
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Acute pancreatitis in pregnancy.妊娠合并急性胰腺炎。
Acta Obstet Gynecol Scand. 2011 Jun;90(6):671-6. doi: 10.1111/j.1600-0412.2011.01072.x. Epub 2011 Mar 4.
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Hypertriglyceridemic pancreatitis: presentation and management.高甘油三酯血症性胰腺炎:临床表现与管理
Am J Gastroenterol. 2009 Apr;104(4):984-91. doi: 10.1038/ajg.2009.27. Epub 2009 Mar 17.

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