意大利门诊胃肠外抗菌药物治疗方式随时间的变化：两个时间段的比较
Changing modalities of outpatient parenteral antimicrobial therapy use over time in Italy: a comparison of two time periods.
作者信息
Esposito Silvano, Noviello Silvana, Boccia Giovanni, De Simone Giuseppe, Pagliano Pasquale, De Caro Francesco
机构信息
Department of Infectious Diseases, University of Salerno, Salerno, Italy.
Department of Hygiene, University of Salerno, Salerno, Italy.
出版信息
Infez Med. 2016 Jun 1;24(2):137-9.
This study aimed to assess the extent and nature of recent changes in the management of outpatient parenteral antimicrobial therapy (OPAT) in Italy. We reviewed our previously reported data from 1999 to 2003 and compared them with data from patients who received OPAT from 2005 to 2010. Data for 1175 patients who received OPAT were analysed. Skin and soft tissue infections (SSTIs) were the most common infection treated with OPAT in both time periods, but an increase in patients with SSTIs receiving OPAT was observed. By contrast, a decline over time of OPAT use was found for patients affected by pneumonia. Furthermore, ceftriaxone use declined, whereas teicoplanin increased over time. In conclusion, OPAT use has significantly changed over time in Italy.
本研究旨在评估意大利门诊胃肠外抗菌治疗（OPAT）管理近期变化的程度和性质。我们回顾了之前报告的1999年至2003年的数据，并将其与2005年至2010年接受OPAT治疗的患者数据进行比较。对1175例接受OPAT治疗的患者数据进行了分析。皮肤和软组织感染（SSTIs）是两个时间段内接受OPAT治疗最常见的感染类型，但接受OPAT治疗的SSTIs患者数量有所增加。相比之下，肺炎患者使用OPAT的情况随时间呈下降趋势。此外，头孢曲松的使用量下降，而替考拉宁的使用量随时间增加。总之，意大利OPAT的使用情况随时间发生了显著变化。
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