Osuagwu Uchechukwu L, Suheimat Marwan, Atchison David A
Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):3422-8. doi: 10.1167/iovs.16-19267.
To investigate mirror symmetry of peripheral ocular aberrations in fellow eyes of iso- and anisomyopes.
Peripheral aberration was measured over the central 42° × 32° visual field for a 5-mm pupil in both eyes of 19 isomyopic (spherical equivalent refraction M [right/left]: -2.5 ± 2.1 diopters [D]/-2.7 ± 2.3 D) and 10 anisomyopic (M: -4.0 ± 1.8 D/-4.3 ± 2.8 D) young adults. Isomyopes had less than 1.0 D fellow eye refraction difference and anisomyopes had between 1.0 D and 2.6 D fellow eye differences (mean difference: 1.3 ± 0.6 D). Orthogonal regression of Zernike coefficients determined right-left eye correlations in isomyopes. For anisomyopes, higher and lower myopic eye coefficients were compared.
For isomyopes, the percentages of visual field locations with significant coefficient correlations between fellow eyes varied from 100% for astigmatism ( ) to 18% for tetrafoil ( ). Positive correlations were found for , , , , , and , and negative correlations were found for , , , , and coefficients, indicating that the signs are different for corresponding locations of fellow eyes for the last five of these coefficients. Slopes of correlations were not different from ± 1, except for , , and (+0.95, -0.97, and +0.52, respectively). In anisomyopes, significant but small fellow eye differences were found for only and coefficients, with significant interactions between anisometropia and field position for only two coefficients.
Peripheral aberration coefficients across the visual field show mirror symmetry in isomyopes, and in a pooled data set the coefficients with negative correlations require sign changes for left eye data. Anisometropia contributes no more to peripheral aberration differences between fellow eyes than could be expected on the basis of refraction differences between people.
研究等屈光度和不等屈光度近视患者双眼周边眼像差的镜像对称性。
对19例等屈光度（球镜等效屈光力M[右/左]：-2.5±2.1屈光度[D]/-2.7±2.3 D）和10例不等屈光度（M：-4.0±1.8 D/-4.3±2.8 D）的年轻成年人双眼，在5mm瞳孔下测量中央42°×32°视野范围内的周边像差。等屈光度患者双眼屈光力差值小于1.0 D，不等屈光度患者双眼屈光力差值在1.0 D至2.6 D之间（平均差值：1.3±0.6 D）。通过对泽尼克系数进行正交回归分析，确定等屈光度患者双眼的左右眼相关性。对于不等屈光度患者，比较高度近视和低度近视眼的系数。
对于等屈光度患者，双眼之间系数具有显著相关性的视野位置百分比，从散光时的100%（）到四叶草像差时的18%（）不等。对于、、、、和系数发现正相关，对于、、、和系数发现负相关，这表明对于这些系数中的后五个，双眼相应位置的符号不同。相关性斜率除了、和（分别为+0.95、-0.97和+0.52）外，均与±1无差异。在不等屈光度患者中，仅和系数发现双眼之间存在显著但较小的差异，仅两个系数在屈光参差和视野位置之间存在显著交互作用。
等屈光度患者整个视野的周边像差系数呈现镜像对称，在合并数据集中，具有负相关性的系数需要对左眼数据进行符号改变。屈光参差对等双眼周边像差差异的影响，并不比基于人群屈光差异所预期的更大。
