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链霉素耳毒性的家族聚集性:常染色体显性遗传?

Familial aggregation of streptomycin ototoxicity: autosomal dominant inheritance?

作者信息

Viljoen D L, Sellars S L, Beighton P

出版信息

J Med Genet. 1983 Oct;20(5):357-60. doi: 10.1136/jmg.20.5.357.

DOI:10.1136/jmg.20.5.357
PMID:6644766
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1049149/
Abstract

Eight members of a large kindred of mixed ancestry from a remote rural area of South Africa were investigated for deafness. In each, severe permanent perceptive hearing loss had developed during antituberculous therapy with streptomycin sulphate in conventional doses. Although unproven by the data available in this study, the familial aggregation and pattern of distribution of sensitivity to streptomycin suggested autosomal dominant inheritance.

摘要

对来自南非偏远农村地区的一个有混合血统的大家族中的8名成员进行了耳聋调查。他们每个人在接受常规剂量硫酸链霉素抗结核治疗期间都出现了严重的永久性感音神经性听力损失。尽管本研究现有数据尚未证实,但对链霉素敏感性的家族聚集性和分布模式提示为常染色体显性遗传。

相似文献

1
Familial aggregation of streptomycin ototoxicity: autosomal dominant inheritance?链霉素耳毒性的家族聚集性:常染色体显性遗传?
J Med Genet. 1983 Oct;20(5):357-60. doi: 10.1136/jmg.20.5.357.
2
[Familial occurrence of hearing loss following streptomycin (SM) treatment].[链霉素(SM)治疗后听力损失的家族性发生情况]
Otolaryngol Pol. 2001;55(3):313-5.
3
Familial incidence of streptomycin hearing loss and hereditary weakness of the cochlea.链霉素所致听力损失的家族发病率及耳蜗遗传性衰弱
Audiology. 1971 Sep-Dec;10(5):315-22. doi: 10.3109/00206097109072568.
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Familial streptomycin ototoxicity in a South African family: a mitochondrial disorder.一个南非家庭中的家族性链霉素耳毒性:一种线粒体疾病。
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Am J Dis Child. 1974 Feb;127(2):245-7. doi: 10.1001/archpedi.1974.02110210095014.
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Unique inheritance of streptomycin-induced deafness.链霉素所致耳聋的独特遗传方式。
Clin Genet. 1989 Jun;35(6):433-6.
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Congenital deaf mutism following streptomycin therapy to mother during pregnancy. A case of streptomycin ototoxicity in utero.孕期母亲接受链霉素治疗后出现的先天性聋哑。一例子宫内链霉素耳毒性病例。
Indian J Chest Dis. 1969 Jan;11(1):51-3.
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[A pedigree analysis of aminoglycoside antibiotic ototoxicity in 43 families].[43个家庭中氨基糖苷类抗生素耳毒性的系谱分析]
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The causes of profound deafness in childhood. In: Sensorinerual hearing loss.儿童深度耳聋的病因。载于:感音神经性听力损失
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Ototoxicity in 626 patients with pulmonary tuberculosis treated with dihydrostreptomycin, streptomycin sulphate, or a combination of both.626例接受双氢链霉素、硫酸链霉素或两者联合治疗的肺结核患者的耳毒性。
Scand J Respir Dis. 1972;53(1):44-50.

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Hearing Impairment in South Africa and the Lessons Learned for Planetary Health Genomics: A Systematic Review.南非的听力障碍及对行星健康基因组学的启示:系统综述。
OMICS. 2022 Jan;26(1):2-18. doi: 10.1089/omi.2021.0181.
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Protective Effects of Deferoxamine on Vestibulotoxicity in Gentamicin-Induced Bilateral Vestibulopathy Rat Model.去铁胺对庆大霉素诱导的双侧前庭病大鼠模型前庭毒性的保护作用
Front Neurol. 2021 Mar 24;12:650752. doi: 10.3389/fneur.2021.650752. eCollection 2021.
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A rapid method for detection of five known mutations associated with aminoglycoside-induced deafness.一种检测与氨基糖苷类药物致聋相关的五种已知突变的快速方法。
BMC Med Genet. 2009 Jan 13;10:2. doi: 10.1186/1471-2350-10-2.
5
Familial streptomycin ototoxicity in a South African family: a mitochondrial disorder.一个南非家庭中的家族性链霉素耳毒性:一种线粒体疾病。
J Med Genet. 1997 Nov;34(11):904-6. doi: 10.1136/jmg.34.11.904.
6
Experimental, clinical and preventive aspects of ototoxicity.耳毒性的实验、临床及预防方面
Eur Arch Otorhinolaryngol. 1994;251(7):375-92. doi: 10.1007/BF00181963.
7
Genetic aspects of antibiotic induced deafness: mitochondrial inheritance.抗生素致聋的遗传学因素:线粒体遗传
J Med Genet. 1991 Feb;28(2):79-83. doi: 10.1136/jmg.28.2.79.

本文引用的文献

1
FAMILIAL SENSITIVITY TO STREPTOMYCIN.家族性对链霉素的敏感性。
J Laryngol Otol. 1964 Nov;78:1037-43. doi: 10.1017/s0022215100063131.
2
Streptomycin ototoxicity in the unborn child.未出生胎儿的链霉素耳毒性。
S Afr Med J. 1981 Aug 22;60(8):316-8.
3
[On the ototoxicity of streptomycin].[论链霉素的耳毒性]
Pract Otorhinolaryngol (Basel). 1966;28(5):305-22.
4
Iatrogenic deafness.
J Laryngol Otol. 1970 Oct;84(10):967-1000. doi: 10.1017/s0022215100072790.
5
Familial occurrence of drug-induced hearing loss.药物性听力损失的家族性发病情况。
Am J Dis Child. 1974 Feb;127(2):245-7. doi: 10.1001/archpedi.1974.02110210095014.