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Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence.

作者信息

Dawson David W, Fernandez-Zapico Martin E

机构信息

Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.

Schulze Center for Novel Therapeutics, Mayo Clinic, Rochester, Minnesota.

出版信息

Gastroenterology. 2016 Aug;151(2):234-7. doi: 10.1053/j.gastro.2016.06.032. Epub 2016 Jun 29.

DOI:10.1053/j.gastro.2016.06.032
PMID:27374366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6042851/
Abstract
摘要

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本文引用的文献

1
Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells.在小鼠胰腺肿瘤切除术后给予吉西他滨可诱导自然杀伤细胞介导的抗肿瘤免疫反应。
Gastroenterology. 2016 Aug;151(2):338-350.e7. doi: 10.1053/j.gastro.2016.05.004. Epub 2016 May 20.
2
Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.利用化疗药物的免疫调节特性提高癌症免疫治疗的成功率。
Front Immunol. 2015 Oct 7;6:516. doi: 10.3389/fimmu.2015.00516. eCollection 2015.
3
Bench to bedside: NK cells and control of metastasis.从实验室到临床：NK 细胞与转移控制。
Clin Immunol. 2017 Apr;177:50-59. doi: 10.1016/j.clim.2015.10.001. Epub 2015 Oct 23.
4
Contrasting Effects of the Cytotoxic Anticancer Drug Gemcitabine and the EGFR Tyrosine Kinase Inhibitor Gefitinib on NK Cell-Mediated Cytotoxicity via Regulation of NKG2D Ligand in Non-Small-Cell Lung Cancer Cells.细胞毒性抗癌药物吉西他滨和表皮生长因子受体酪氨酸激酶抑制剂吉非替尼通过调节非小细胞肺癌细胞中的NKG2D配体对自然杀伤细胞介导的细胞毒性产生的对比作用
PLoS One. 2015 Oct 6;10(10):e0139809. doi: 10.1371/journal.pone.0139809. eCollection 2015.
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Pancreatic cancer: from state-of-the-art treatments to promising novel therapies.胰腺癌：从最先进的治疗方法到有前途的新疗法。
Nat Rev Clin Oncol. 2015 Jun;12(6):319-34. doi: 10.1038/nrclinonc.2015.53. Epub 2015 Mar 31.
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Pancreas. 2015 Apr;44(3):386-93. doi: 10.1097/MPA.0000000000000288.
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Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.预计 2030 年美国癌症发病与死亡人数：甲状腺癌、肝癌和胰腺癌带来的意外负担。
Cancer Res. 2014 Jun 1;74(11):2913-21. doi: 10.1158/0008-5472.CAN-14-0155.
10
Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial.吉西他滨辅助化疗与可切除胰腺癌患者长期结局：CONKO-001 随机试验。
JAMA. 2013 Oct 9;310(14):1473-81. doi: 10.1001/jama.2013.279201.