Kotlęga Dariusz, Gołąb-Janowska Monika, Masztalewicz Marta, Ciećwież Sylwester, Nowacki Przemysław
Department of Neurology, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Department of Neurology, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Neurol Neurochir Pol. 2016 Jul-Aug;50(4):265-70. doi: 10.1016/j.pjnns.2016.03.006. Epub 2016 Mar 23.
Stroke is the second leading cause of death worldwide, and the leading cause of acquired disability in adults in most regions. There have been distinguished modifiable and non-modifiable risk factors of stroke. Among them the emotional stress was presented as a risk factor. The aim of this review was to present available data regarding the influence of acute and chronic mental stress on the risk of ischemic stroke as well as discussing the potential pathomechanisms of such relationship. There is an evident association between both acute and chronic emotional stress and risk of stroke. Several potential mechanisms are discussed to be the cause. Stress can increase the cerebrovascular disease risk by modulating symphaticomimetic activity, affecting the blood pressure reactivity, cerebral endothelium, coagulation or heart rhythm. The emotional stress seems to be still underestimated risk factor in neurological practice and research. Further studies and analyses should be provided for better understanding of this complex, not fully known epidemiological problem.
中风是全球第二大致死原因，也是大多数地区成年人后天残疾的主要原因。中风存在显著的可改变和不可改变的风险因素。其中，情绪压力被视为一种风险因素。本综述的目的是呈现关于急性和慢性精神压力对缺血性中风风险影响的现有数据，并讨论这种关系的潜在病理机制。急性和慢性情绪压力与中风风险之间存在明显关联。讨论了几种可能的机制作为原因。压力可通过调节拟交感神经活动、影响血压反应性、脑内皮、凝血或心律来增加脑血管疾病风险。在神经学实践和研究中，情绪压力似乎仍是一个被低估的风险因素。应进行进一步的研究和分析，以更好地理解这个复杂的、尚未完全了解的流行病学问题。
