膝关节周围骨巨细胞瘤治疗中肿瘤刮除术与切除术的比较。
Comparison of tumor curettage and resection for treatment of giant cell tumor of the bone around the knee joint.
作者信息
Zhang Sheng, Zhang Jianhua, Wang Xin
机构信息
Sheng Zhang, Department of Orthopedics, Yan'an People's Hospital, Yan'an 716000, Shanxi Province, China.
Jianhua Zhang, Department of Orthopedics, the Affiliated Hospital of Yan'an University, Yan'an 716000, Shanxi Province, China.
出版信息
Pak J Med Sci. 2016 May-Jun;32(3):662-6. doi: 10.12669/pjms.323.9654.
OBJECTIVE
To analyze the efficacies of tumor curettage and resection for treatment of giant cell tumor of the bone (GCTB) around the knee joint (KJ).
METHODS
A total of 126 KJ-GCTB cases were treated at our department from August 2011 to February 2015. These cases were divided into two groups (A and B) according to treatment methods. Group A underwent tumor curettage, while group B underwent tumor resection.
RESULTS
The relapse rates did not differ significantly between the groups (P>0.05), while the complication rate in group A was significantly lower than that in group B (P<0.05). In addition, the Enneking score for group A was significantly higher than that for group B (P<0.05); in addition, postoperative local recurrence, histopathological grading according to Jaffe, and radiographic imaging-based Campanacci's staging positively correlated (P<0.05).
CONCLUSION
Tumor curettage was the preferred surgical approach for patients with KJ-GCTB.
目的
分析刮除术与切除术治疗膝关节周围骨巨细胞瘤（GCTB）的疗效。
方法
2011年8月至2015年2月，我科共治疗126例膝关节周围骨巨细胞瘤患者。根据治疗方法将这些病例分为两组（A组和B组）。A组行肿瘤刮除术，B组行肿瘤切除术。
结果
两组复发率差异无统计学意义（P>0.05），而A组并发症发生率显著低于B组（P<0.05）。此外，A组的Enneking评分显著高于B组（P<0.05）；此外，术后局部复发、根据Jaffe进行的组织病理学分级以及基于影像学的Campanacci分期呈正相关（P<0.05）。
结论
刮除术是膝关节周围骨巨细胞瘤患者的首选手术方式。
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