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Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment.

作者信息

Krejci Jan, Mlejnek Dalibor, Sochorova Dana, Nemec Petr

机构信息

Department of Cardiovascular Diseases, St. Anne's University Hospital-International Clinical Research Center, Pekarska 53, 65691 Brno, Czech Republic; International Clinical Research Center and Masaryk University, Brno, Czech Republic.

International Clinical Research Center and Masaryk University, Brno, Czech Republic.

出版信息

Biomed Res Int. 2016;2016:4087632. doi: 10.1155/2016/4087632. Epub 2016 Jun 12.


DOI:10.1155/2016/4087632
PMID:27382566
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4921131/
Abstract

Inflammatory cardiomyopathy is defined as inflammation of the heart muscle associated with impaired function of the myocardium. In our region, its etiology is most often viral. Viral infection is a possible trigger of immune and autoimmune mechanisms which contributed to the damage of myocardial function. Myocarditis is considered the most common cause of dilated cardiomyopathy. Typical manifestation of this disease is heart failure, chest pain, or arrhythmias. The most important noninvasive diagnostic method is magnetic resonance imaging, but the gold standard of diagnostics is invasive examination, endomyocardial biopsy. In a significant proportion of cases with impaired left ventricular systolic function, recovery occurs spontaneously in several weeks and therefore it is appropriate to postpone critical therapeutic decisions about 3-6 months after start of the treatment. Therapy is based on standard heart failure treatment; immunosuppressive or antimicrobial treatment may be considered in some cases depending on the results of endomyocardial biopsy. If severe dysfunction of the left ventricle persists, device therapy may be needed.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/e4b1dd8adb60/BMRI2016-4087632.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/c2a6e10596c5/BMRI2016-4087632.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/e7426f0e33a5/BMRI2016-4087632.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/df4dee685907/BMRI2016-4087632.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/e4b1dd8adb60/BMRI2016-4087632.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/c2a6e10596c5/BMRI2016-4087632.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/e7426f0e33a5/BMRI2016-4087632.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/df4dee685907/BMRI2016-4087632.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27c6/4921131/e4b1dd8adb60/BMRI2016-4087632.004.jpg

相似文献

[1]
Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment.

Biomed Res Int. 2016

[2]
[Myocarditis and inflammatory cardiomyopathy].

Vnitr Lek. 2017

[3]
[Inflammatory myocardial disease].

Vnitr Lek. 2019

[4]
[Indication for myocardial biopsy in myocarditis and dilated cardiomyopathy].

Med Klin (Munich). 2005-9-15

[5]
[Myocarditis and inflammatory cardiomyopathy--current treatment options].

Dtsch Med Wochenschr. 2016-1

[6]
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Rev Esp Cardiol (Engl Ed). 2024-8

[7]
Update on Myocarditis and Inflammatory Cardiomyopathy: Reemergence of Endomyocardial Biopsy.

Rev Esp Cardiol (Engl Ed). 2016-2

[8]
[Diagnosis and treatment of inflammatory heart diseases: role of endomyocardial biopsy].

Herz. 2006-6

[9]
Inflammatory dilated cardiomyopathy (DCMI).

Herz. 2005-9

[10]
[Myocarditis and dilated cardiomyopathy in children. Old questions-- new answers].

Lijec Vjesn. 1999

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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
The Role of MicroRNAs in Dilated Cardiomyopathy: New Insights for an Old Entity.

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[10]
A Novel Clinical Score for Differential Diagnosis Between Acute Myocarditis and Acute Coronary Syndrome - The SAlzburg MYocarditis (SAMY) Score.

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本文引用的文献

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J Cardiovasc Med (Hagerstown). 2016-8

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