Laboratorio de Fisiologia Digestiva y Motilidad, Instituto de Investigaciones Medico Biologicas, Veracruz, Mexico.
Laboratorio de Fisiologia Digestiva y Motilidad, Instituto de Investigaciones Medico Biologicas, Veracruz, Mexico
BMJ Case Rep. 2020 Jul 8;13(7):e235135. doi: 10.1136/bcr-2020-235135.
Pemphigus is a rare autoimmune disease that causes blistering of the skin and oral mucosa. In bullous pemphigoid (BP), skin involvement is predominant, whereas oesophageal involvement is rare, compared with other blistering diseases. We present, herein, the case of a 67-year-old man with a history of successfully treated BP that 2 years later developed progressive dysphagia, unintentional weight loss and iron deficiency anaemia. An endoscopy with biopsies was performed, and its findings were consistent with 'sloughing esophagitis' (esophagitis dissecans superficialis) associated with BP. Oesophageal involvement was present during the first weeks, making our case unusual due to the isolated oesophageal symptoms that developed 24 months later.
天疱疮是一种罕见的自身免疫性疾病，可导致皮肤和口腔黏膜起疱。在大疱性类天疱疮（BP）中，皮肤受累为主，而与其他起疱性疾病相比，食管受累罕见。我们在此介绍 1 例 67 岁男性病例，该患者有成功治疗的 BP 病史，2 年后出现进行性吞咽困难、非自愿性体重减轻和缺铁性贫血。进行了内镜检查和活检，结果与 BP 相关的“脱落性食管炎”（表层松解性食管炎）一致。食管受累发生在最初几周，由于 24 个月后出现孤立性食管症状，使我们的病例变得不寻常。
