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3 岁中国儿童的眼部生物测量参数:可测性、分布及与人体测量参数的关系。

Ocular biometric parameters among 3-year-old Chinese children: testability, distribution and association with anthropometric parameters.

机构信息

Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.

Maternal and Child Healthcare Hospital of Yuhua District, Nanjing, 210012 China.

出版信息

Sci Rep. 2016 Jul 7;6:29577. doi: 10.1038/srep29577.

Abstract

This survey was conducted to determine the testability, distribution and associations of ocular biometric parameters in Chinese preschool children. Ocular biometric examinations, including the axial length (AL) and corneal radius of curvature (CR), were conducted on 1,688 3-year-old subjects by using an IOLMaster in August 2015. Anthropometric parameters, including height and weight, were measured according to a standardized protocol, and body mass index (BMI) was calculated. The testability was 93.7% for the AL and 78.6% for the CR overall, and both measures improved with age. Girls performed slightly better in AL measurements (P = 0.08), and the difference in CR was statistically significant (P < 0.05). The AL distribution was normal in girls (P = 0.12), whereas it was not in boys (P < 0.05). For CR1, all subgroups presented normal distributions (P = 0.16 for boys; P = 0.20 for girls), but the distribution varied when the subgroups were combined (P < 0.05). CR2 presented a normal distribution (P = 0.11), whereas the AL/CR ratio was abnormal (P < 0.001). Boys exhibited a significantly longer AL, a greater CR and a greater AL/CR ratio than girls (all P < 0.001).

摘要

本研究旨在调查中国学龄前儿童眼生物测量参数的可测性、分布和相关性。2015 年 8 月,使用 IOLMaster 对 1688 名 3 岁儿童进行了眼生物测量检查,包括眼轴(AL)和角膜曲率半径(CR)。根据标准化方案测量了身高和体重等人体测量参数,并计算了体重指数(BMI)。AL 的可测性总体为 93.7%,CR 为 78.6%,且两者均随年龄增长而提高。女孩在 AL 测量中表现略好(P=0.08),而 CR 的差异具有统计学意义(P<0.05)。AL 的分布在女孩中呈正态(P=0.12),而在男孩中则不然(P<0.05)。对于 CR1,所有亚组均呈正态分布(男孩 P=0.16;女孩 P=0.20),但当亚组组合时分布则不同(P<0.05)。CR2 呈正态分布(P=0.11),而 AL/CR 比值异常(P<0.001)。与女孩相比,男孩的 AL 更长,CR 更大,AL/CR 比值也更大(均 P<0.001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c4b/4935861/96f0a90ddd69/srep29577-f1.jpg

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