Kassim Said Abasse, James Peter Bai, Alolga Rachel Nammahime, Assanhou Assogba Gabin, Kassim Said Mohamed, Bacar Anfane, Silai Rahamatou, Tian Lei, Li Hongchao, Ma Aixia
School of International Economics and Trade, China Pharmaceutical University, Nanjing, China; Department of Internal Medicine - Gastroenterology, Southern Medical University, Guangzhou, China.
S Afr Med J. 2016 Jun 17;106(7):709-14. doi: 10.7196/SAMJ.2016.v106i7.10902.
Malaria remains a public health challenge in sub-Saharan Africa. In response to this, many countries are working towards achieving the World Health Assembly and Roll Back Malaria Partnership target of a 75% decline in malaria incidence.
To assess trends in malaria morbidity and mortality in the three islands of the Comoros Archipelago from 2010 to 2014.
This was a retrospective study in which all confirmed malaria cases and deaths recorded between 2010 and 2014 were accessed from the national malaria control database. Trends and comparisons in malaria incidence and case fatality rates for all age groups, including under-5 children and pregnant women, were analysed using Microsoft Excel and SPSS version 16.
A substantial decline in malaria incidence was observed for each island between 2010 and 2014; from 75.98 cases per 1 000 population in 2010 to 0.14 in 2014 in Moheli, 60.60 to 0.02 in Anjouan and 235.36 to 5.47 in Grand Comoro. Additionally, a general reduction in malaria case fatalities was observed. In Moheli, there were no case fatalities between 2010 and 2014, while there was a decline in the case fatality rate in Anjouan (from 1.20 fatalities per 1 000 cases to 0) and Grand Comoros (0.51 to 0). There were also significant differences (p<0.05) in malaria incidence and case fatalities between the three islands. A similar trend was observed for pregnant women and under-5 children.
Our study indicates a significant decline in malaria morbidity and mortality in the islands of Moheli, Anjouan and Grand Comoro from 2010 to 2014. This considerable reduction is attributed to a combination of malaria prevention and control interventions implemented during the study period.
疟疾仍是撒哈拉以南非洲地区的一项公共卫生挑战。对此，许多国家正在努力实现世界卫生大会及遏制疟疾伙伴关系提出的将疟疾发病率降低75%的目标。
评估2010年至2014年科摩罗群岛三个岛屿的疟疾发病率和死亡率趋势。
这是一项回顾性研究，从国家疟疾控制数据库中获取2010年至2014年期间记录的所有确诊疟疾病例和死亡病例。使用Microsoft Excel和SPSS 16版软件对所有年龄组（包括5岁以下儿童和孕妇）的疟疾发病率和病死率进行趋势分析和比较。
2010年至2014年期间，每个岛屿的疟疾发病率均大幅下降；莫埃利岛从2010年的每1000人口75.98例降至2014年的0.14例，昂儒昂岛从60.60例降至0.02例，大科摩罗岛从235.36例降至5.47例。此外，疟疾病死率普遍下降。在莫埃利岛，2010年至2014年期间无病例死亡，而昂儒昂岛的病死率有所下降（从每1000例1.20例死亡降至0），大科摩罗岛的病死率从0.51降至0。三个岛屿之间的疟疾发病率和病死率也存在显著差异（p<0.05）。孕妇和5岁以下儿童也呈现类似趋势。
我们的研究表明，2010年至2014年期间，莫埃利岛、昂儒昂岛和大科摩罗岛的疟疾发病率和死亡率显著下降。这一显著降低归因于研究期间实施的疟疾预防和控制干预措施的综合作用。
