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食管癌的导演式个体化治疗。

Stage-directed individualized therapy in esophageal cancer.

机构信息

Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.

Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.

出版信息

Ann N Y Acad Sci. 2016 Oct;1381(1):50-65. doi: 10.1111/nyas.13113. Epub 2016 Jul 6.

DOI:10.1111/nyas.13113
PMID:27384385
Abstract

Esophageal cancer is the eighth most common cancer worldwide, and the incidence of esophageal carcinoma is rapidly increasing. With the advent of new staging and treatment techniques, esophageal cancer can now be managed through various strategies. A good understanding of the advances and limitations of new staging techniques and how these can guide in individualizing treatment is important to improve outcomes for esophageal cancer patients. This paper outlines the recent progress in staging and treatment of esophageal cancer, with particularly attention to endoscopic techniques for early-stage esophageal cancer, multimodality treatment for locally advanced esophageal cancer, assessment of response to neoadjuvant treatment, and the role of cervical lymph node dissection. Furthermore, advances in robot-assisted surgical techniques and postoperative recovery protocols that may further improve outcomes after esophagectomy are discussed.

摘要

食管癌是全球第八大常见癌症,食管癌的发病率正在迅速上升。随着新的分期和治疗技术的出现,现在可以通过多种策略来治疗食管癌。深入了解新分期技术的进展和局限性,以及如何根据这些技术来制定个体化治疗方案,对于改善食管癌患者的预后非常重要。本文概述了食管癌分期和治疗的最新进展,特别关注早期食管癌的内镜技术、局部晚期食管癌的多模态治疗、新辅助治疗反应的评估以及颈淋巴结清扫术的作用。此外,还讨论了机器人辅助手术技术和术后恢复方案的进展,这些可能会进一步提高食管癌手术后的疗效。

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1
Stage-directed individualized therapy in esophageal cancer.食管癌的导演式个体化治疗。
Ann N Y Acad Sci. 2016 Oct;1381(1):50-65. doi: 10.1111/nyas.13113. Epub 2016 Jul 6.
2
Personalizing therapy for esophageal cancer patients.为食管癌患者进行个体化治疗。
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3
Radiation dose does not influence anastomotic complications in patients with esophageal cancer treated with neoadjuvant chemoradiation and transhiatal esophagectomy.对于接受新辅助放化疗和经裂孔食管切除术治疗的食管癌患者,辐射剂量并不影响吻合口并发症。
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Neoadjuvant chemoradiation versus chemotherapy for patients undergoing esophagectomy for esophageal cancer.新辅助放化疗与单纯化疗用于接受食管癌切除术的患者的比较。
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