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1型糖尿病发病时婴儿出现血小板减少相关性多器官功能衰竭，经新鲜冰冻血浆治疗成功。

Thrombocytopenia-associated multiorgan failure occurring in an infant at the onset of type 1 diabetes successfully treated with fresh frozen plasma.

作者信息

Kumar Revati, McSharry Brent, Bradbeer Peter, Wiltshire Esko, Jefferies Craig

机构信息

University College London London WC1E 6BT UK.

Department of Pediatric Intensive care Starship Children's Hospital Auckland New Zealand.

出版信息

Clin Case Rep. 2016 Jun 2;4(7):671-4. doi: 10.1002/ccr3.587. eCollection 2016 Jul.

DOI:10.1002/ccr3.587
PMID:27386126
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4929803/
Abstract

TAMOF is a devastating microangiopathy that can occur in association with the new onset of T1DM, and should be considered with the onset of thrombocytopenia, renal failure, and raised LDH. Treatment with fresh frozen plasma should be considered as a first-line option in such cases prior to plasma exchange.

摘要

血栓性微血管病性溶血性贫血（TAMOF）是一种严重的微血管病，可与1型糖尿病的新发相关，当出现血小板减少、肾衰竭和乳酸脱氢酶升高时应予以考虑。在进行血浆置换之前，此类病例应首先考虑使用新鲜冷冻血浆进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89af/4929803/56daeefd5a17/CCR3-4-671-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89af/4929803/56daeefd5a17/CCR3-4-671-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89af/4929803/56daeefd5a17/CCR3-4-671-g001.jpg

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Pediatr Crit Care Med. 2014 Oct;15(8):e354-9. doi: 10.1097/PCC.0000000000000227.
2
HUS and TTP in Children.儿童中的溶血尿毒综合征和血栓性血小板减少性紫癜。
Pediatr Clin North Am. 2013 Dec;60(6):1513-26. doi: 10.1016/j.pcl.2013.08.007.
3
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