Elias A N, Domurat E S, Friis R, Valenta L J
J Natl Med Assoc. 1989 Apr;81(4):357-62.
Blood flow in a segment of the leg was determined by bioimpedance plethysmography in 47 diabetic patients and in 19 normal volunteers. The blood flow through the limb, expressed as stroke volume/m2 (SV/m2), was not significantly different in the two populations. SV/m2 showed significant negative correlation with the presence of peripheral vascular disease, fasting serum cholesterol concentration, glycosylated hemoglobin (HbA1c) concentration, and the duration of diabetes. The presence or absence of retinopathy (27.7% of cases) or nephropathy (4.3% of cases) did not show strong association with the SV/m2. Neither the duration of the hypertension nor the systolic or diastolic blood pressure correlated significantly with blood flow in the extremity. These data suggest that only some of the parameters used to assess "control" of diabetic patients can be useful predictors of macrovascular as well as microvascular disease in diabetic patients.
采用生物电阻抗体积描记法测定了47例糖尿病患者和19名正常志愿者腿部某一部位的血流情况。以每平方米体表面积的每搏输出量（SV/m2）表示的肢体血流量在两组人群中无显著差异。SV/m2与外周血管疾病的存在、空腹血清胆固醇浓度、糖化血红蛋白（HbA1c）浓度以及糖尿病病程呈显著负相关。视网膜病变（27.7%的病例）或肾病（4.3%的病例）的有无与SV/m2无强烈关联。高血压病程以及收缩压或舒张压与肢体血流均无显著相关性。这些数据表明，用于评估糖尿病患者“控制情况”的参数中，只有部分可作为糖尿病患者大血管和微血管疾病的有效预测指标。
