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一名多发性骨髓瘤患者发生了莱氏 Diplodia 属真菌性骨髓炎。

Lasiodiplodia species fungal osteomyelitis in a multiple myeloma patient.

作者信息

Mohan M, Shalin S C, Kothari A, Rico J C C, Caradine K, Burgess M

机构信息

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

出版信息

Transpl Infect Dis. 2016 Oct;18(5):761-764. doi: 10.1111/tid.12573. Epub 2016 Sep 9.

Abstract

Lasiodiplodia species are environmental fungi that have been reported as a cause of infection in both immunocompetent and immunocompromised patients. We present a case of fungal osteomyelitis caused by Lasiodiplodia species in a patient with multiple myeloma after autologous stem cell transplant. The patient was successfully treated with a combination of surgery and oral voriconzole. To the best of our knowledge, this is the first reported case of fungal osteomyelitis caused by Lasiodiplodia species.

摘要

炭角菌属是环境真菌,在免疫功能正常和免疫功能低下的患者中均有报道可引起感染。我们报告了1例自体干细胞移植后多发性骨髓瘤患者发生的由炭角菌属引起的真菌性骨髓炎。该患者通过手术和口服伏立康唑联合治疗成功治愈。据我们所知,这是首例由炭角菌属引起的真菌性骨髓炎的报道病例。

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