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因脐部感染导致的腹膜透析相关性腹膜炎

Peritoneal dialysis-associated peritonitis due to infected umbilicus.

作者信息

Wattanasatja Veerapat, Phisutrattanaporn Jarubut, Doenphai Natchaporn, Sirinual Sirirat, Kanjanabuch Talerngsak

机构信息

Department of Internal Medicine, Sunpasitthiprasong Hospital, Ubon Ratchathani, Thailand.

Department of Internal Medicine, Sukhothai Hospital, Sukhothai, Thailand.

出版信息

Med Mycol Case Rep. 2024 Jun 12;45:100654. doi: 10.1016/j.mmcr.2024.100654. eCollection 2024 Sep.

Abstract

We provide the first case report of peritoneal dialysis (PD)-associated peritonitis due to , a known plant pathogen causing rotting and dieback in post-harvest citrus fruit, in immunocompetent patient with fungal colonization inside the PD catheter lumen. A root cause analysis suspected the patient's umbilical infection as the source of contamination. The fungal infection was established through microscopic examination of the PD catheter lumen and galactomannan testing in both serum and effluent. The species of pathogen was confirmed by DNA barcoding. The patient responded well to timely PD catheter removal and a 2-week course of oral voriconazole. Preventive strategies should prioritize hygiene practices, including umbilical care, to mitigate the risk of contamination and subsequent infections of fungal pathogens.

摘要

我们报告了首例与腹膜透析(PD)相关的腹膜炎病例,病原体为 ,一种已知的植物病原体,可导致收获后的柑橘类水果腐烂和枯萎,该病例发生在一名免疫功能正常但PD导管腔内有真菌定植的患者身上。根本原因分析怀疑患者的脐部感染是污染源。通过对PD导管腔进行显微镜检查以及对血清和流出液进行半乳甘露聚糖检测确诊了真菌感染。通过DNA条形码技术确认了病原体的种类。患者对及时拔除PD导管以及为期2周的口服伏立康唑疗程反应良好。预防策略应优先考虑卫生措施,包括脐部护理,以降低真菌病原体污染及后续感染的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2172/11245899/9ed876ab5e1c/gr1.jpg

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