Bennett Maxwell R, Hatton Sean, Hermens Daniel F, Lagopoulos Jim
Brain & Mind Centre, University of Sydney, Camperdown, NSW 2050, Australia.
Brain & Mind Centre, University of Sydney, Camperdown, NSW 2050, Australia; Sunshine Coast Mind and Neuroscience - Thompson Institute, Birtinya, QLD, Australia.
Prog Neurobiol. 2016 Oct-Nov;145-146:1-25. doi: 10.1016/j.pneurobio.2016.07.001. Epub 2016 Jul 5.
Cognitive neuroscientists in the late 20th century began the task of identifying the part(s) of the brain concerned with normal behavior as manifest in the psychological capacities as affective powers, reasoning, behaving purposively and the pursuit of goals, following introduction of the 'functional magnetic resonance imaging' (fMRI) method for identifying brain activity. For this research program to be successful two questions require satisfactory answers. First, as the fMRI method can currently only be used on stationary subjects, to what extent can neuropsychological tests applicable to such stationary subjects be correlated with normal behavior. Second, to what extent can correlations between the various neuropsychological tests on the one hand, and sites of brain activity determined with fMRI on the other, be regarded as established. The extent to which these questions have yet received satisfactory answers is reviewed, and suggestions made both for improving correlations of neuropsychological tests with behavior as well as with the results of fMRI-based observations.
20世纪末，认知神经科学家开始了一项任务，即在引入用于识别大脑活动的“功能磁共振成像”（fMRI）方法之后，确定大脑中与正常行为相关的部分，这些正常行为表现为情感能力、推理、有目的的行为和目标追求等心理能力。要使这个研究项目取得成功，有两个问题需要得到令人满意的答案。首先，由于fMRI方法目前只能用于静止的受试者，适用于此类静止受试者的神经心理学测试在多大程度上能够与正常行为相关联。其次，一方面，各种神经心理学测试之间的相关性，与另一方面通过fMRI确定的大脑活动部位之间的相关性，在多大程度上可以被视为已确立。本文回顾了这些问题在多大程度上得到了令人满意的答案，并提出了一些建议，以改善神经心理学测试与行为以及基于fMRI观察结果之间的相关性。
