Tharp B R, Scher M S, Clancy R R
Division of Pediatric Neurology, Stanford University Medical Center, California 94305.
Neuropediatrics. 1989 May;20(2):64-72. doi: 10.1055/s-2008-1071267.
Serial EEGs were recorded during the postnatal period from 62 infants with birth weights less than or equal to 1200 gms. Neurological examinations were performed in proximity to the EEG and each infant had at least one imaging study of the brain in the immediate postnatal period. All infants were examined at 2-3 years age. Neurological sequelae were seen in all infants with markedly abnormal neonatal EEGs and in the majority of those with persistently moderately abnormal tracings. A particularly unique EEG abnormality consisting of an arrest of maturation of cerebral electrical activity was seen in infants with bronchopulmonary dysplasia who suffered neurological sequelae. A persistently asymmetric EEG background was recorded in infants with hemispheric pathology who were found to have hemisyndromes at long term follow-up. Serial EEGs were better predictors of long term outcome than imaging studies and the neurological examination.
对62名出生体重小于或等于1200克的婴儿在出生后进行了系列脑电图（EEG）记录。在EEG检查前后进行了神经学检查，并且每个婴儿在出生后即刻至少进行了一次脑部影像学检查。所有婴儿在2至3岁时接受了检查。在所有新生儿EEG明显异常的婴儿以及大多数EEG持续中度异常的婴儿中均发现了神经后遗症。在患有神经后遗症的支气管肺发育不良婴儿中，观察到一种特别独特的EEG异常，即脑电活动成熟停滞。在半球病变的婴儿中记录到持续不对称的EEG背景，这些婴儿在长期随访中被发现患有偏瘫综合征。系列EEG比影像学检查和神经学检查更能预测长期预后。
