Papa C M
N J Med. 1989 May;86(5):361-5.
Although few actinic keratoses eventuate as squamous cell carcinomas, these precancerous lesions cannot be ignored. A medical regimen of topical tretinoin use and sun protection appears to be effective in treating and preventing these precancers, with the added cosmetic benefits of ameliorating the alterations which accompany sun damage on exposed skin.
尽管很少有光化性角化病最终发展为鳞状细胞癌，但这些癌前病变不能被忽视。局部使用维甲酸和防晒的医疗方案似乎对治疗和预防这些癌前病变有效，还有改善暴露皮肤因阳光损伤而出现的变化这一额外的美容益处。
