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极低频电磁场:一种用于脊髓损伤康复的可能的非侵入性治疗工具。

Extremely low-frequency electromagnetic fields: A possible non-invasive therapeutic tool for spinal cord injury rehabilitation.

作者信息

Kumar Suneel, Dey Soumil, Jain Suman

机构信息

a Department of Physiology , All India Institute of Medical Sciences , New Delhi , India.

b W. M. Keck Center for Collaborative Neuroscience, Rutgers, The State University of New Jersey , Piscataway , NJ , USA.

出版信息

Electromagn Biol Med. 2017;36(1):88-101. doi: 10.1080/15368378.2016.1194290. Epub 2016 Jul 11.

DOI:10.1080/15368378.2016.1194290
PMID:27399648
Abstract

Traumatic insults to the spinal cord induce both immediate mechanical damage and subsequent tissue degeneration. The latter involves a range of events namely cellular disturbance, homeostatic imbalance, ionic and neurotransmitters derangement that ultimately result in loss of sensorimotor functions. The targets for improving function after spinal cord injury (SCI) are mainly directed toward limiting these secondary injury events. Extremely low-frequency electromagnetic field (ELF-EMF) is a possible non-invasive therapeutic intervention for SCI rehabilitation which has the potential to constrain the secondary injury-induced events. In the present review, we discuss the effects of ELF-EMF on experimental and clinical SCI as well as on biological system.

摘要

脊髓受到创伤性损伤会导致即时的机械性损伤以及随后的组织退化。后者涉及一系列事件,即细胞紊乱、体内平衡失调、离子和神经递质紊乱,最终导致感觉运动功能丧失。改善脊髓损伤(SCI)后功能的目标主要是针对限制这些继发性损伤事件。极低频电磁场(ELF-EMF)是一种可能用于SCI康复的非侵入性治疗干预措施,它有可能抑制继发性损伤引发的事件。在本综述中,我们讨论了ELF-EMF对实验性和临床SCI以及生物系统的影响。

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