心力衰竭患者的身体成分与骨密度
Body Composition and Bone Mineral Density in Patients With Heart Failure.
作者信息
Abshire Demetrius A, Moser Debra K, Clasey Jody L, Chung Misook L, Pressler Susan J, Dunbar Sandra B, Heo Seongkum, Lennie Terry A
机构信息
1 Washington State University College of Nursing, Spokane, WA, USA.
2 University of Kentucky College of Nursing, Lexington, KY, USA.
出版信息
West J Nurs Res. 2017 Apr;39(4):582-599. doi: 10.1177/0193945916658885. Epub 2016 Jul 11.
The purpose of this study was to examine associations among bone mineral density, osteopenia/osteoporosis, body mass index (BMI), and body composition in patients with heart failure (HF). A total of 119 patients (age = 61 ± 12 years, 65% male) underwent dual-energy X-ray absorptiometry scans to determine bone mineral density and body composition. In multivariable linear regressions, BMI, relative skeletal muscle index (RSMI), and mineral-free lean mass were positively associated with total body bone mineral density. Mineral-free lean mass was most strongly associated with bone mineral density (β = .398). In multivariable logistic regressions, higher BMI, RSMI, and mineral-free lean mass were associated with lower odds for osteopenia/osteoporosis. Fat mass was not associated with total body bone mineral density or osteopenia/osteoporosis. These results suggest that muscle mass may be the important component of body mass associated with bone mineral density in patients with HF.
本研究的目的是探讨心力衰竭（HF）患者的骨矿物质密度、骨质减少/骨质疏松症、体重指数（BMI）和身体成分之间的关联。共有119名患者（年龄 = 61±12岁，65%为男性）接受了双能X线吸收测定扫描，以确定骨矿物质密度和身体成分。在多变量线性回归中，BMI、相对骨骼肌指数（RSMI）和去矿化瘦体重与全身骨矿物质密度呈正相关。去矿化瘦体重与骨矿物质密度的相关性最强（β = 0.398）。在多变量逻辑回归中，较高的BMI、RSMI和去矿化瘦体重与较低的骨质减少/骨质疏松症几率相关。脂肪量与全身骨矿物质密度或骨质减少/骨质疏松症无关。这些结果表明，肌肉量可能是HF患者中与骨矿物质密度相关的体重的重要组成部分。
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