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福岛第一核电站事故后疏散人群中与生活方式相关疾病的研究:对川内村的一项长期随访回顾性研究

Lifestyle-related diseases following the evacuation after the Fukushima Daiichi nuclear power plant accident: a retrospective study of Kawauchi Village with long-term follow-up.

作者信息

Ebner Daniel K, Ohsawa Megumi, Igari Keiko, Harada Kouji H, Koizumi Akio

机构信息

Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan Brown University Alpert Medical School, Providence, Rhode Island, USA.

Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

出版信息

BMJ Open. 2016 Jul 11;6(7):e011641. doi: 10.1136/bmjopen-2016-011641.

DOI:10.1136/bmjopen-2016-011641
PMID:27401362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4947762/
Abstract

OBJECTIVES

Kawauchi Village lies 20 km west of the Fukushima Daiichi nuclear power plant. On 16 March 2011, evacuation was ordered due to the threat of radiological exposure, and was lifted in April 2012. In this study, we aimed to evaluate the predisaster and postdisaster health status of the Kawauchi Villagers, measured by routine yearly physical examinations.

METHODS

We analysed the annual health examination data of residents of Kawauchi Village from 2008 to 2013, as available from the Japanese National Health Insurance system. Data from 2011 were not available due to the disaster. Since the health data included the same participants repeatedly from year to year, the sample was non-independent and generalised estimated equation modelling was used. A predisaster time period (2008-2010) was categorised for comparison with postdisaster 2012 and 2013. The outcome examined was the prevalence of metabolic disease, and was adjusted for confounding factors.

RESULTS

Data for 20.6%-25.9% of the total residents were available in this period. In 2013, the prevalence of metabolic syndrome (from 17.0% to 25.2%, p<0.001), diabetes (from 11.3% to 17.0%, p<0.001), dyslipidaemia (from 43.2% to 56.7%, p<0.0001), hyperuricaemia (from 5.2% to 8.4%, p=0.006) and chronic kidney disease (from 16.1% to 26.7%, p<0.001) was found to be elevated significantly compared to predisaster years, while that of obesity or hypertension did not change.

CONCLUSIONS

The present follow-up study for Kawauchi Village revealed an increase in lifestyle-related disease following the March 2011 disaster and subsequent evacuation, and this trend still continues 2 years later.

摘要

目的

川内村位于福岛第一核电站以西20公里处。2011年3月16日,因存在辐射暴露威胁而发布了疏散命令,并于2012年4月解除。在本研究中,我们旨在通过常规年度体检来评估川内村村民灾前和灾后的健康状况。

方法

我们分析了2008年至2013年川内村居民的年度健康检查数据,这些数据来自日本国民健康保险系统。由于灾害原因,2011年的数据无法获取。由于健康数据每年都包含相同的参与者,样本不独立,因此使用了广义估计方程模型。将灾前时间段(2008 - 2010年)进行分类,以便与2012年和2013年的灾后情况进行比较。所检查的结果是代谢性疾病的患病率,并对混杂因素进行了调整。

结果

在此期间可获得全村20.6% - 25.9%居民的数据。2013年,代谢综合征(从17.0%升至25.2%,p<0.001)、糖尿病(从11.3%升至17.0%,p<0.001)、血脂异常(从43.2%升至56.7%,p<0.0001)、高尿酸血症(从5.2%升至8.4%,p = 0.006)和慢性肾脏病(从16.1%升至26.7%,p<0.001)的患病率与灾前年份相比显著升高,而肥胖或高血压的患病率没有变化。

结论

本次对川内村的随访研究显示,2011年3月的灾难及随后的疏散导致生活方式相关疾病增加,且这种趋势在两年后仍在持续。

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