Tanaka Shun, Nawata Kan, Kitahara Hiroto, Yoshitake Shuichi, Matsuoka Takahiro, Itoda Yoshifumi, Kinoshita Osamu, Kimura Mitsutoshi, Ono Minoru
Department of Cardiac Surgery, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan.
J Artif Organs. 2016 Dec;19(4):387-391. doi: 10.1007/s10047-016-0919-4. Epub 2016 Jul 11.
We successfully controlled infection of a left ventricular assist device by performing pump exchange. A 53-year-old man was implanted with DuraHeart for ischemic cardiomyopathy as a bridge to transplantation. Two years later, he was hospitalized with the diagnosis of driveline infection. The blood cultures detected Pseudomonas aeruginosa. During the admission, he developed brain hemorrhage perhaps due to septic emboli. The chest computed tomography scan revealed a small defect inside the outflow graft of the DuraHeart, which was highly suspected of vegetation. He underwent pump exchange, from DuraHeart to Jarvik 2000 with concomitant omentopexy. His postoperative course was uneventful, and he was discharged with no sequela of the brain hemorrhage. Four months after the pump exchange, he successfully underwent heart transplantation. No infectious tissue was observed in the pericardial space at the time of heart transplantation. Pump exchange is an effective way to manage refractory left ventricular assist device infection, and the timing of surgical intervention is of great importance.
我们通过进行泵更换成功控制了左心室辅助装置的感染。一名53岁男性因缺血性心肌病植入DuraHeart作为移植桥梁。两年后,他因诊断为隧道感染住院。血培养检测到铜绿假单胞菌。住院期间,他可能因脓毒性栓子发生脑出血。胸部计算机断层扫描显示DuraHeart流出道移植物内有一个小缺损,高度怀疑有赘生物。他接受了泵更换,从DuraHeart换成Jarvik 2000并同时进行了网膜固定术。他的术后过程平稳,出院时无脑出血后遗症。泵更换四个月后,他成功接受了心脏移植。心脏移植时在心包腔内未观察到感染组织。泵更换是处理难治性左心室辅助装置感染的有效方法,手术干预的时机至关重要。