Joseph D B, Bauer S B, Colodny A H, Mandell J, Retik A B
Department of Surgery, Children's Hospital, Boston, Massachusetts.
Pediatrics. 1989 Jul;84(1):78-82.
Clean, intermittent catheterization was instituted in 38 babies with myelodysplasia who were thought to be at risk for upper urinary tract deterioration because of neurogenic bladder dysfunction. There were 19 patients 2 weeks to 12 months of age, 11 were 1 to 2 years of age, and 8 were older than 2 years. Effectiveness of clean, intermittent catheterization was determined by maintenance of upper urinary tract stability. Upper urinary tracts improved or remained stable in 13 of 16 infants (81%) with reflux and 16 of 18 infants (89%) with detrusor-sphincter dyssynergia. Bacteriuria was present in 16 (42%), with only 2 infants (5%) having a febrile episode; no infant required hospitalization because of urinary tract infections. No further complications were identified in infants who were cleanly and intermittently catheterized. Most families found clean, intermittent catheterization of their infants easy to master and not stressful, and their children adjusted to it at an early age.
对38例患有脊髓发育不良的婴儿实施了清洁间歇性导尿术，这些婴儿因神经源性膀胱功能障碍被认为存在上尿路恶化的风险。其中19例患者年龄在2周至12个月之间，11例年龄在1至2岁之间，8例年龄超过2岁。通过维持上尿路稳定性来确定清洁间歇性导尿术的有效性。16例有反流的婴儿中有13例（81%）上尿路得到改善或保持稳定，18例有逼尿肌-括约肌协同失调的婴儿中有16例（89%）上尿路得到改善或保持稳定。16例（42%）存在菌尿，只有2例婴儿（5%）出现发热；没有婴儿因尿路感染需要住院治疗。在接受清洁间歇性导尿术的婴儿中未发现进一步的并发症。大多数家庭发现对婴儿进行清洁间歇性导尿术很容易掌握且没有压力，他们的孩子在很小的时候就适应了。
