Nejatinamini Sara, Ataie-Jafari Asal, Ghasemian Anoosheh, Kelishadi Roya, Khajavi Alireza, Kasaeian Amir, Djalalinia Shirin, Saqib Fahad, Majidi Somayye, Abdolmaleki Roxana, Hosseini Mehrnaz, Asayesh Hamid, Qorbani Mostafa
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran .
J Tehran Heart Cent. 2016 Jan 13;11(1):21-9.
Dietary risk factors constitute some of the leading risk factors for cardiovascular disease in Iran. The current study reports the burden of ischemic heart disease (IHD) attributable to a low omega-3 fatty acids intake in Iran using the data of the Global Burden of Disease (GBD) Study 2010.
We used data on Iran for the years 1990, 2005, and 2010 derived from the GBD Study conducted by the Institute for Health Metrics and Evaluation (IHME) in 2010. Using the comparative risk assessment, we calculated the proportion of death, years of life lost, years lived with disability, and disability-adjusted life years (DALYs) caused by IHD attributable to a low omega-3 fatty acids intake in the GBD studies from 1990 to 2010.
In 1990, a dietary pattern low in seafood omega-3 fatty acids intake was responsible for 423 (95% uncertainty interval [UI], 300 to 559), 3000 (95% UI, 2182 to 3840), and 4743 (95% UI, 3280 to 6047) DALYs per 100000 persons in the age groups of 15 to 49 years, 50 to 69 years, and 70+ years - respectively - in both sexes. The DALY rates decreased to 250 (95% UI, 172 to 331), 2078 (95% UI, 1446 to 2729), and 3911 (95% UI, 2736 to 5142) in 2010. The death rates per 100000 persons in the mentioned age groups were 9 (95% UI, 6 to 12), 113 (95% UI, 82 to 144), and 366 (95% UI, 255 to 469) in 1990 versus 6 (95% UI, 4 to 7), 76 (95% UI, 53 to 99), and 344 (95% UI, 241 to 453) in 2010. The burden of IHD attributable to diet low in seafood omega-3 was 1.3% (95% UI, 0.97 to 1.7) of the total DALYs in 1990 and 2.0% (95% UI, 1.45 to 2.63) in 2010 for Iran.
The findings of the GBD Study 2010 showed a declining trend in the burden of IHD attributable to a low omega-3 fatty acids intake in a period of 20 years. Additional disease burden studies at national and sub-national levels in Iran using more data sources are suggested for public health priorities and planning public health strategies.
饮食风险因素是伊朗心血管疾病的一些主要风险因素。本研究利用2010年全球疾病负担（GBD）研究的数据，报告了伊朗因ω-3脂肪酸摄入量低导致的缺血性心脏病（IHD）负担。
我们使用了健康指标与评估研究所（IHME）2010年进行的GBD研究中1990年、2005年和2010年伊朗的数据。通过比较风险评估，我们计算了1990年至2010年GBD研究中因ω-3脂肪酸摄入量低导致的IHD所造成的死亡比例、寿命损失年数、带病生存年数和伤残调整生命年（DALYs）。
1990年，海产品ω-3脂肪酸摄入量低的饮食模式导致15至49岁、50至69岁和70岁及以上年龄组每10万人中分别有423（95%不确定区间[UI]，300至559）、3000（95%UI，2182至3840）和4743（95%UI，3280至6047）个DALYs，男女皆是如此。2010年，DALY率降至250（95%UI，172至331）、2078（95%UI，1446至2729）和3911（95%UI，2736至5142）。上述年龄组每10万人的死亡率在1990年分别为9（95%UI，6至12）、113（95%UI，82至144）和366（95%UI，255至469），而在2010年分别为6（95%UI，4至7）、76（95%UI，53至99）和344（95%UI，241至453）。2010年，伊朗因海产品ω-3含量低的饮食导致的IHD负担占总DALYs的1.3%（95%UI，0.97至1.7），1990年为2.0%（95%UI，1.45至2.63）。
2010年GBD研究结果显示，在20年时间里，因ω-3脂肪酸摄入量低导致的IHD负担呈下降趋势。建议在伊朗国家和次国家层面利用更多数据源进行额外的疾病负担研究，以确定公共卫生重点并规划公共卫生战略。
