Wong S M, Wong M M, Seligmann O, Wagner H
Planta Med. 1989 Jun;55(3):276-80. doi: 10.1055/s-2006-962003.
Two new naphtho-pyrone glycosides, 9-[(beta-D-glucopyranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]-10- hydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1 -one (5) and 6-[(alpha-apiofuranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]- rubrofusarin (6), together with cassiaside (3) and rubrofusarin-6-beta-gentiobioside (4) were isolated from the seeds of Cassia tora L. Their structures were elucidated on the basis of chemical and spectral data. The naphtho-gamma-pyrone glycosides (3, 4, and 6) were found to have significant hepato-protective effects against galactosamine damage, which were higher than that of silybin from Silybum marianum.
从决明子种子中分离出两种新的萘并吡喃酮糖苷，9-[(β-D-吡喃葡萄糖基-(1→6)-O-β-D-吡喃葡萄糖基)氧基]-10-羟基-7-甲氧基-3-甲基-1H-萘并[2,3-c]吡喃-1-酮(5)和6-[(α-阿糖呋喃糖基-(1→6)-O-β-D-吡喃葡萄糖基)氧基]-红镰菌素(6)，以及决明子苷(3)和红镰菌素-6-β-龙胆二糖苷(4)。根据化学和光谱数据阐明了它们的结构。发现萘并γ-吡喃酮糖苷(3、4和6)对氨基半乳糖损伤具有显著的肝保护作用，其作用高于水飞蓟宾。
