N-取代 β(2)-高丙氨酸低聚物：具有主链手性的肽缩醛。
Oligomers of N-Substituted β(2)-Homoalanines: Peptoids with Backbone Chirality.
机构信息
Departments of Chemistry and Advanced Material Science, Pohang University of Science and Technology (POSTECH) , Pohang 37673, South Korea.
Department of Chemistry, Chonnam National University , Gwangju 61186, South Korea.
出版信息
Org Lett. 2016 Aug 5;18(15):3678-81. doi: 10.1021/acs.orglett.6b01726. Epub 2016 Jul 12.
PMID:27404658
Abstract
A new class of peptoid-based peptidomimetics composed of oligomers of N-substituted β(2)-homoalanines is reported. Design, solid-phase synthesis, and preliminary circular dichroism studies of oligomers of N-alkylated β(2)-homoalanines consisting of up to 8-mers are described.
摘要
报告了一类新型的基于肽的拟肽化合物，由 N-取代的β(2)-高丙氨酸的低聚物组成。描述了由多达 8 个单体组成的 N-烷基化β(2)-高丙氨酸低聚物的设计、固相合成和初步圆二色性研究。
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