Rolschau J
Acta Obstet Gynecol Scand Suppl. 1978;72:11-4.
A study has been made of a prospectively selected material of circumvallate placentae; the latter being defined as an elevated edge of more than 50% of the circumference. The material consists of 447 placentae from liveborn singleton infants, where 287 were from exemplary pregnancies, and 160 from births with a gestational age (GA) of less than 266 days and/or a birth weight of less than 2750 g. The material was prospectively randomized. It was divided into clinical groups according to the GA and under-weight. Nineteen circumvallate placentae were found. Among these were more multigravidae and more with pre-gestational menstrual irregularity than expected. The number of antepartum haemorrhages was as expected. There were more premature infants, premature under-weight infants and under-weight infants than expected. Nine of the 20 premature under-weight infants in the material had circumvallate placenta. In relation to a previously published basic material, it was found that the birth weight, and placental content of RNA and DNA were significantly reduced. It is concluded that placentae with more than 50% circumvallation are associated with prematurity and under-weight, as well as a placenta with fewer cells than normal. The genesis of the anomaly is discussed.
对前瞻性选择的轮状胎盘材料进行了一项研究；后者被定义为边缘隆起超过周长50%。该材料包括447例活产单胎婴儿的胎盘，其中287例来自典型妊娠，160例来自孕周（GA）小于266天和/或出生体重小于2750g的分娩。该材料进行了前瞻性随机分组。根据孕周和体重不足情况分为临床组。发现19例轮状胎盘。其中经产妇和妊娠前月经不规律者比预期更多。产前出血的数量与预期相符。早产、早产低体重和低体重婴儿比预期更多。该材料中20例早产低体重婴儿中有9例有轮状胎盘。与之前发表的基础材料相比，发现出生体重以及胎盘RNA和DNA含量显著降低。结论是边缘隆起超过50%的胎盘与早产、低体重以及细胞数量比正常少的胎盘有关。讨论了该异常的发生机制。
