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在无氧气分析仪的情况下通过氧气头罩对新生儿进行FiO₂控制治疗。

Controlled FiO2 Therapy to Neonates by Oxygenhood in the Absence of Oxygen Analyzer.

作者信息

Jatana S K, Dhingra S, Nair Mng, Gupta G

机构信息

Senior Advisor (Paediatrics), 151 Base Hospital, C/o 99 APO.

Graded Specialist (Paediatrics), Military Hospital, Golconda.

出版信息

Med J Armed Forces India. 2007 Apr;63(2):149-53. doi: 10.1016/S0377-1237(07)80061-X. Epub 2011 Jul 21.

Abstract

BACKGROUND

A study was conducted to evaluate a system of standardizing the oxygen concentration inside the oxygen hood and to develop guidelines for controlled FiO2 administration by changing size of the hood, lid position on the hood and the oxygen flow rate, without an oxygen analyzer. The effect of low flow rates on carbon dioxide (CO2) retention was also studied.

METHOD

A dummy patient and thirty neonates, requiring oxygen to be delivered through head box, constituted the material for the study group. Oxygen content in the head box was measured using a standard oxygen analyzer while the size of head box, flow rate and lid position were changed independently and in combination. The head boxes were tested on a dummy patient. These results were analyzed, and applied to thirty neonates requiring oxygen therapy using a head box.

RESULT

Volume of headbox had an inverse relation with the oxygen concentration inside the headbox and smaller sized headbox achieved more predictable oxygen concentration at all flow rates. Maximum difference in oxygen concentration by varying the lid position was seen in the large headbox. Keeping the variables constant, oxygen concentration was significantly lower in babies as compared to dummy. No significant CO2 retention was found at a flow rate of four litres per minute (lpm) in small and three lpm in a medium and large head box respectively, while lower flow rates were associated with CO2 retention.

CONCLUSION

It is possible to predict the oxygen concentration inside the head box without the use of oxygen analyzer. Larger head box and higher lid position, results in lower oxygen concentration, at a given oxygen flow rate. Oxygen concentration achieved in babies is lesser than the concentration achieved in a dummy. Flow rates of less than four lpm in small and three lpm in medium and large sized head boxes are associated with CO2 retention. These results are not applicable to infants weighing less than 2 kg.

摘要

背景

开展了一项研究,旨在评估一种用于规范氧气头罩内氧气浓度的系统,并通过改变头罩尺寸、头罩上盖子的位置以及氧气流速,在不使用氧气分析仪的情况下制定控制吸氧浓度(FiO2)给药的指南。还研究了低流速对二氧化碳(CO2)潴留的影响。

方法

一名模拟患者和30名需要通过头罩吸氧的新生儿构成了研究组的材料。使用标准氧气分析仪测量头罩内的氧气含量,同时对头罩尺寸、流速和盖子位置进行独立及组合改变。对头罩在模拟患者上进行测试。分析这些结果,并将其应用于30名需要使用头罩进行氧疗的新生儿。

结果

头罩体积与头罩内氧气浓度呈反比,较小尺寸的头罩在所有流速下都能实现更可预测的氧气浓度。在大型头罩中,通过改变盖子位置观察到氧气浓度的最大差异。在保持变量不变的情况下,与模拟患者相比,婴儿体内的氧气浓度显著更低。在小尺寸头罩中,每分钟4升(lpm)的流速、中尺寸和大尺寸头罩中每分钟3升的流速下未发现明显的CO2潴留,而较低的流速与CO2潴留相关。

结论

不使用氧气分析仪也有可能预测头罩内的氧气浓度。在给定的氧气流速下,较大的头罩和较高的盖子位置会导致较低的氧气浓度。婴儿体内达到的氧气浓度低于模拟患者。小尺寸头罩中流速低于每分钟4升、中尺寸和大尺寸头罩中流速低于每分钟3升与CO2潴留相关。这些结果不适用于体重小于2千克的婴儿。

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Oxygen administration in infants.婴儿吸氧
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The oxygen radical disease in neonatology.新生儿科中的氧自由基疾病。
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