Ramji Siddarth, Saugstad Ola D, Jain Ashish
Department of Neonatology, Maulana Azad Medical College, New Delhi, 110002, India,
Indian J Pediatr. 2015 Jan;82(1):46-52. doi: 10.1007/s12098-014-1571-8. Epub 2014 Oct 18.
Use of high oxygen concentrations in treating neonatal illness has been challenged in the past few decades. In the face of evidence suggesting adverse outcomes (both clinical and biochemical) with use of high oxygen concentrations, the current guidelines appear to favour use of the lowest possible concentrations of oxygen for the shortest time to treat ill neonates. Current delivery room guidelines recommend using room air when initiating positive pressure ventilation during resuscitation. Targeting appropriate oxygen saturation when delivering supplemental oxygen, both in the delivery room and neonatal intensive care unit (NICU), are now the new emerging standards in neonatal care. Investments in good quality pulse oximeters and oxygen blenders in neonatal care units is now seen as critical to improve newborn survival.
在过去几十年中，使用高氧浓度治疗新生儿疾病受到了挑战。面对使用高氧浓度会带来不良后果（包括临床和生化方面）的证据，当前指南似乎倾向于在治疗患病新生儿时使用尽可能低的氧浓度，并在最短时间内使用。当前产房指南建议在复苏期间开始正压通气时使用室内空气。在产房和新生儿重症监护病房（NICU）提供补充氧气时，以适当的血氧饱和度为目标，现在已成为新生儿护理的新出现标准。在新生儿护理单元投资高质量的脉搏血氧仪和氧气混合器，现在被视为提高新生儿存活率的关键。
