Koraluru Munegowda, Nandigam Manideep, Bairy Indira, Vidyasagar Sudha, Varma Muralidhar
Lecturer, Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Intern, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Trop Doct. 2017 Jan;47(1):67-69. doi: 10.1177/0049475516658400. Epub 2016 Jul 13.
Eschar in scrub typhus aids in early diagnosis and institution of appropriate therapy; however, the eschar positivity rates vary greatly in endemic regions. Multiple eschars in scrub typhus are a rare presentation. Our patient presented with fever and multiple eschars and was empirically started on doxycycline. Nested polymerase chain reaction from all the four eschars and from EDTA blood were positive for 56-kDa type-specific antigen which is specific for Orientia tsutsugamushi The patient recovered completely after 7 days of antibiotic treatment. He was from an area where scrub typhus was not observed previously. An eschar in an acute febrile patient from the "tsutsugamushi triangle" is a valuable sign in scrub typhus diagnosis. A search for multiple eschars in scrub typhus must be made by clinicians.
恙虫病中的焦痂有助于早期诊断并启动适当治疗;然而,在流行地区焦痂阳性率差异很大。恙虫病出现多个焦痂的情况较为罕见。我们的患者表现出发热和多个焦痂,经验性地开始使用多西环素治疗。对所有四个焦痂以及乙二胺四乙酸抗凝血进行巢式聚合酶链反应,结果显示56-kDa型特异性抗原呈阳性,该抗原对恙虫东方体具有特异性。患者在接受抗生素治疗7天后完全康复。他来自一个此前未观察到恙虫病的地区。来自“恙虫病三角区”的急性发热患者身上出现的焦痂是恙虫病诊断中的一个重要体征。临床医生必须留意恙虫病患者身上是否有多个焦痂。