Jansen E H, van den Berg R H, Both-Miedema R, van Blitterswijk H, Stephany R W
National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Vet Q. 1989 Apr;11(2):87-93. doi: 10.1080/01652176.1989.9694204.
The second part of an experiment is described in which 20 one year old bulls were injected with diethylstilbestrol (DES) dipropionate containing preparations. Analysis of DES content was performed in several tissues, such as the injection site, diaphragm muscle, psoas muscle, liver, kidney and bile. In the injection site appreciable amounts of DES were found. Measurable amounts of DES were also found in liver and kidney until 4 weeks after injection. In bile, DES concentrations were even higher than those in urine, and were well correlated with DES concentrations in urine. Implications for screening purposes are discussed.
给20头一岁大的公牛注射含己烯雌酚二丙酸酯的制剂。对几个组织进行了己烯雌酚含量分析，这些组织包括注射部位、膈肌、腰大肌、肝脏、肾脏和胆汁。在注射部位发现了相当数量的己烯雌酚。在肝脏和肾脏中也发现了可测量的己烯雌酚含量，直至注射后4周。在胆汁中，己烯雌酚浓度甚至高于尿液中的浓度，并且与尿液中的己烯雌酚浓度高度相关。文中还讨论了其在筛查目的方面的意义。
