Ouédraogo A S, Zaré C, Traoré I A, Sanou S, Sanon B G, Ki B, Poda A, Kambou T
Laboratoire de bactériologie, centre hospitalier universitaire Souro Sanou, 01 BP 676 Bobo Dioulasso 01, Burkina Faso.
Service de chirurgie générale, centre hospitalier universitaire Souro Sanou, Burkina Faso.
Med Sante Trop. 2016 May 1;26(2):203-6. doi: 10.1684/mst.2016.0555.
The purpose of this study was to describe the microbiological characteristics of community-acquired peritonitis at the Souro Sanou teaching hospital of Bobo Dioulasso, Burkina Faso. This 10-month prospective study, from July 2012 through May 2013 included all cases of community-acquired peritonitis who underwent surgery at our hospital and had a pus sample taken at that time. Bacteriological analyses were performed according to the hospital laboratory's protocol. The study included 72 patients (45 men and 27 women with a sex-ratio of 1.6). Their mean age was 27.3 years (range: 14 months to 67 years). The analysis of 72 samples of pus enabled confirmation of 39 cases and led to the identification of 53 bacterial strains. The most common families were enterobacteriaceae in 58% and Gram-positive cocci in 36%. The most common enterobacteria species was Escherichia coli (47%) followed by Streptococcus species (22%). The microbiological confirmation of peritonitis was most frequent in the 20-30 year-old age group. These bacteria appeared most susceptible to gentamycin, ceftriaxone, and ciprofloxacin, while we observed resistance to amoxicillin and the combination of clavulanic acid-amoxicillin. These findings suggest that the best probabilistic antibiotic treatment for the peritonitis in our context would combine a third-generation cephalosporin with aminoglycosides, with imidazole to cover potential anaerobic bacteria.
本研究的目的是描述布基纳法索博博迪乌拉索苏罗萨努教学医院社区获得性腹膜炎的微生物学特征。这项为期10个月的前瞻性研究，从2012年7月至2013年5月，纳入了所有在我院接受手术且当时采集了脓液样本的社区获得性腹膜炎病例。细菌学分析按照医院实验室的方案进行。该研究纳入了72例患者（45名男性和27名女性，性别比为1.6）。他们的平均年龄为27.3岁（范围：14个月至67岁）。对72份脓液样本的分析证实了39例病例，并鉴定出53株细菌菌株。最常见的菌属是肠杆菌科（58%）和革兰氏阳性球菌（36%）。最常见的肠杆菌种类是大肠杆菌（47%），其次是链球菌属（22%）。腹膜炎的微生物学确诊在20至30岁年龄组最为常见。这些细菌似乎对庆大霉素、头孢曲松和环丙沙星最敏感，而我们观察到对阿莫西林以及克拉维酸 - 阿莫西林组合存在耐药性。这些发现表明，在我们的情况下，针对腹膜炎的最佳概率性抗生素治疗应将第三代头孢菌素与氨基糖苷类药物联合使用，并加用咪唑以覆盖潜在的厌氧菌。
