Iushmanov V E, Kotrikadze N G, Pershin A D, Dzhishkariani O S, Tsartsidze M A
Vopr Onkol. 1989;35(5):560-4.
High-resolution 1H-NMR (360 MHz) combined with thin-layer chromatography was used to study profile and molecular structure changes of inverted micelles of human blood developing in patients with malignant and benign tumors of the breast and uterus. Alterations were demonstrated in relative intensities of some lipid NMR peaks in tumor, as compared to normal blood. Changes in blood lipid levels, e.g. cholesterol, in tumor affect lipid structural and dynamical status thus elucidating NMR regularities obtained.
采用高分辨率1H-NMR（360 MHz）结合薄层色谱法，研究乳腺癌和子宫良恶性肿瘤患者体内人血反相胶束的分布和分子结构变化。与正常血液相比，肿瘤中一些脂质NMR峰的相对强度出现了改变。肿瘤中血脂水平的变化，如胆固醇，会影响脂质的结构和动态状态，从而阐明所获得的NMR规律。
