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[乳腺癌和子宫癌患者血脂中的磷脂成分]

[Phospholipid composition of blood lipids in breast and uterine cancer].

作者信息

Kotrikadze N G, Tsartsidze M A, Dzhishkariani O S, Londaridze A M, Lomsadze B A

出版信息

Eksp Onkol. 1987;9(2):68-70.

PMID:3582245
Abstract

A comparative analysis of quantitative changes in phospholipids, as well as peroxidation of undiluted blood lipids, plasma and blood cells in healthy women, those suffering from breast and uterus cancer, and from nonmalignant tumours (breast fibroadenoma and uterus fibroma) does not show any specific regularity typical of only malignant neoplasma and not typical of nonmalignant ones. Disturbances in the balance of negative charge phospholipids are supposed to change the electrostatic interaction in the lipid-protein complexes of supramolecular structures during the malignant growth.

摘要

对健康女性、患有乳腺癌和子宫癌的女性以及患有非恶性肿瘤(乳腺纤维瘤和子宫纤维瘤)的女性的磷脂定量变化以及未稀释血脂、血浆和血细胞的过氧化进行比较分析,未发现仅恶性肿瘤特有的、非恶性肿瘤不具有的任何特定规律。负电荷磷脂平衡的紊乱被认为会在恶性生长过程中改变超分子结构的脂蛋白复合物中的静电相互作用。

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