Coe C J
Yonsei Med J. 1989;30(1):81-7. doi: 10.3349/ymj.1989.30.1.81.
Guillain-Barre syndrome is known as one of the autoimmune disease, but the etiology, pathophysiology relating immune reaction, as well as the treatment are not established. It still causes physical handicap although its rate is low. The causes, clinical symptoms and outcome of 132 cases of Guillain-Barre syndrome have been analyzed. The patients' ages ranged from 4 months to 15 years. The antecedent events for 56.1% of the patients were known. These were upper respiratory tract infection, unexplained fever, vomiting, diarrhea, vaccination, measles, german measles, shigellosis, mumps, hepatitis, pertussis and surgery in order of frequency. The CSF protein level reached a maximum at 12.3 +/- 9.5 days. Steroids did not influence the outcome of this disease. More studies are necessary to conquer the disease.
吉兰-巴雷综合征是一种自身免疫性疾病，但病因、与免疫反应相关的病理生理学以及治疗方法尚未明确。尽管其导致身体残疾的几率较低，但仍会造成身体残疾。对132例吉兰-巴雷综合征患者的病因、临床症状及预后进行了分析。患者年龄从4个月至15岁不等。56.1%的患者有前驱事件，按发生频率依次为上呼吸道感染、不明原因发热、呕吐、腹泻、疫苗接种、麻疹、风疹、志贺菌病、腮腺炎、肝炎、百日咳及手术。脑脊液蛋白水平在12.3±9.5天达到最高值。类固醇对该病的预后无影响。需要进行更多研究以攻克该病。
