Piłkowska E
Neurol Neurochir Pol. 1981 Jan-Feb;15(1):31-7.
The dynamics of neurological changes was analysed in 34 cases of Guillain-Barré syndrome from the standpoint of the influence of selected factors on late effects of the disease. The level of CSF protein at the time of maximal intensity of the symptoms reflected the dynamics of the disease, but had no prognostic importance. The duration of the acute phase had an effect on late results but was modified by treatment with steroids. On the basis of partial correlations of the studied material it was found that the higher was the dose of steroids given in the acute phase of the disease the lower was the degree of permanent damage to the peripheral nervous system. This suggests that the most effective method was administration of steroids in high daily doses and the duration of this treatment should be made dependent on the course and the intensity of the acute phase in a given case.
从某些选定因素对格林-巴利综合征后遗症的影响角度，分析了34例格林-巴利综合征患者神经学变化的动态情况。症状最严重时脑脊液蛋白水平反映了疾病的动态变化，但并无预后意义。急性期的持续时间对后期结果有影响，但可通过类固醇治疗加以改变。根据所研究资料的偏相关性发现，疾病急性期给予的类固醇剂量越高，周围神经系统永久性损伤的程度越低。这表明最有效的方法是每日给予高剂量类固醇，且该治疗的持续时间应根据具体病例的急性期病程和严重程度而定。
