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[不同保存液中红细胞浓缩物流变学特性与6周储存期的比较研究]

[Comparative studies of rheologic properties of erythrocyte concentrates in relation to a 6-week storage period in various preservative solutions].

作者信息

Barras J P, Jung T, Haberthür C, Koerner K

出版信息

Vasa. 1989;18(2):122-7.

PMID:2741533
Abstract

Buffycoat free red cell concentrates were stored at 4 degrees C for 42 days in CPD-A1 and two new red cell preservation solutions, PAGGS-Sorbitol and SAG-Mannitol. The rheological behaviour of the red cells was measured by viscometry of red cell suspensions (hematocrit 45%) at steady flow at various intervals during the storage period. The viscoelastic properties of the red cells were studied at oscillatory flow using an oscillation rheometer. The deformability of the red cells during storage was determined by measurement of the viscosity of hard packed cells at steady flow. The results show better red cell deformability during the entire storage period using the new solutions PAGGS-Sorbitol or SAG-Mannitol compared to the standard blood bank preservation solution CPD-A1.

摘要

去除白膜层的红细胞浓缩液分别在CPD - A1以及两种新型红细胞保存液PAGGS - 山梨醇和SAG - 甘露醇中于4℃储存42天。在储存期间的不同时间间隔,通过对红细胞悬液(血细胞比容45%)在稳定流动状态下进行粘度测定来测量红细胞的流变行为。使用振荡流变仪在振荡流动状态下研究红细胞的粘弹性特性。通过测量硬包装细胞在稳定流动状态下的粘度来确定储存期间红细胞的变形性。结果表明,与标准血库保存液CPD - A1相比,使用新型保存液PAGGS - 山梨醇或SAG - 甘露醇时,在整个储存期间红细胞具有更好的变形性。

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