Kubosawa H, Konno A, Komatsu T, Ishige H, Kondo Y
Department of Pathology, School of Medicine, Chiba University, Japan.
Acta Pathol Jpn. 1989 Mar;39(3):212-5. doi: 10.1111/j.1440-1827.1989.tb01503.x.
A case of peliosis hepatis in a 52-year-old woman with unusual involvement of the spleen and lymph nodes is described. The initial sign was intraperitoneal hemorrhage from the splenic lesion, recessitating splenectomy. The hepatic lesion, which was first noticed during the operation, rapidly progressed and eventually resulted in hepatic rupture with fatal intraperitoneal hemorrhage. Serial sections treated by silver impregnation revealed degeneration and dissolution of the fine reticulin framework in the involved organs, suggesting the possible morphogenesis of the peliotic lesion. The patient had no history of any underlying disorders or of medication with steroids.
本文描述了一例52岁女性的肝紫癜病，其脾脏和淋巴结有异常累及。最初的症状是脾部病变导致的腹腔内出血，需行脾切除术。肝脏病变在手术中首次被发现，迅速进展，最终导致肝破裂并伴有致命性腹腔内出血。经银浸染处理的连续切片显示，受累器官内的细网状纤维框架出现变性和溶解，提示了紫癜性病变可能的形态发生机制。该患者无任何基础疾病史，也未使用过类固醇药物。
