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肝紫癜病。一例累及多个器官的罕见病例。

Peliosis hepatis. An unusual case involving multiple organs.

作者信息

Ichijima K, Kobashi Y, Yamabe H, Fujii Y, Inoue Y

出版信息

Acta Pathol Jpn. 1980 Jan;30(1):109-20. doi: 10.1111/j.1440-1827.1980.tb01308.x.

Abstract

The case is that of a 70-year-old Japanese male who had peliosis hepatis with disseminated peliotic lesions in various organs. The initial sign was spontaneous pneumothorax followed by pulmonary hemorrhage. There was no history of anabolic steroid ingestion and his history of pulmonary tuberculosis revealed no pathological changes. Autopsy findings suggested that dilatation of sinusoids with slow progressive injury of sinusoidal endothelium and hepatocytes due to unknown local and general etiologic factors may be an initial mechanism in the development of peliosis hepatis.

摘要

该病例为一名70岁的日本男性,患有肝紫癜病,全身多个器官出现弥漫性紫癜样病变。最初症状为自发性气胸,随后出现肺出血。患者无合成代谢类固醇摄入史,其肺结核病史未显示出病理变化。尸检结果表明,由于未知的局部和全身病因,肝血窦扩张,肝血窦内皮细胞和肝细胞缓慢进行性损伤,可能是肝紫癜病发生的初始机制。

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